The views of David Lewis and the Meinongians are both often met with an incredulous stare. This is not by accident. The stunned disbelief that usually accompanies the stare is a natural first reaction to a large ontology. Indeed, Lewis has been explicitly linked with Meinong, a charge that he has taken great pains to deny. However, the issue is not a simple one. ‘Meinongianism’ is a complex set...

A missense mutation (A385 to T), predicting an Ile129 to Phe substitution, in the human Secretor alpha 1,2-fucosyltransferase gene was present in double dose in Lewis(a+b+) individuals, but not in Lewis(a-b+) individuals. Co-segregation of the Lewis(a+b+) phenotype with homozygosity for the mutation was also verified. These results yield a potential molecular basis for the weak Secretor allele ...

a mild and green method has been developed for the preparation of coumarins derivatives through the one-pot reactions. in our study,various phenols and ethyl acetoacetate compound in which we used silica-supported boron sulfonic acid [sio2/b(so4h)3] as a new, highly efficient and tri-functional inorganic brønsted acid catalyst were processed under solvent-free condition and thermal. the catalys...

Equilibria for the reactions of benzhydryl cations (Ar2CH(+)) with phosphines, tert-amines, pyridines, and related Lewis bases were determined photometrically in CH2Cl2 and CH3CN solution at 20 °C. The measured equilibrium constants can be expressed by the sum of two parameters, defined as the Lewis Acidity (LA) of the benzhydrylium ions and the Lewis basicity (LB) of the phosphines, pyridines,...

A series of fluorophosphonium salts, [R3PF][X] (R = alkyl or aryl; X = FB(C6F5)3, [B(C6F5)4]), have been prepared by reactions of phosphine/borane frustrated Lewis pairs (FLPs) with XeF2 or difluorophosphoranes with [Et3Si][B(C6F5)4]. As the substituents bound to phosphorus become increasingly electron withdrawing, the corresponding fluorophosphonium salts are shown to be increasingly Lewis aci...

The synthesis of several electron poor allenes bearing electron withdrawing substituents is described and their use as Lewis acids in the field of frustrated Lewis pair (FLP) chemistry reported. At room temperature the combination of N-heterocyclic carbenes (NHC) with the allenes under study invariably afforded the corresponding Lewis adducts; however, at -78 °C this reaction is in most of the ...

In recent years 'frustrated Lewis pairs' (FLPs) have been shown to be effective metal-free catalysts for the hydrogenation of many unsaturated substrates. Even so, limited functional-group tolerance restricts the range of solvents in which FLP-mediated reactions can be performed, with all FLP-mediated hydrogenations reported to date carried out in non-donor hydrocarbon or chlorinated solvents. ...

We have done bulk rock compositional analyses (INAA, ICP-MS) and petrologic study of a suite of diogenite meteorites. Most contain orthopyroxenes with mg#s of 70.6– 79.0. Meteorite Hills (MET) 00425 is magnesian (mg# of 83.9). Lewis Cliff (LEW) 88011 contains orthopyroxene grains of varying mg# (76.3–68.6). Queen Alexandra Range (QUE) 93009 (orthopyroxene mg# 70.6) contains coarse-grained norit...

Lewis rats display hyporesponsive hypothalamo-pituitary-adrenocortical (HPA) axes, overproduction of cytokines, and susceptibility to inflammatory disease. The Lewis corticotropin-releasing hormone (CRH) neurosecretory system contains normal numbers of vasopressin (VP)-deficient axon varicosities, but abnormally sparse VP-containing varicosities in the external zone of the median eminence, comp...

BACKGROUND In head and neck squamous cell carcinoma (HNSCC), tumor markers may be helpful to evaluate prognosis accurately as well as to improve therapy selection. Detection of human MUC1 has been widely employed for the evaluation of carcinoma patients. This article aims to study MUC1, Tn, sTn, and Lewis antigenic expression in primary HNSCC, lymph node metastasis, and local recurrences. MET...