Lymphoepithelioma-like cholangiocarcinomas are rare tumors and most of them are related with Epstein-Barr virus (EBV) infection. Here, a case of a patient with lymphoepithelioma-like cholangiocarcinoma not associated with EBV infection is presented. In a 79-year-old man with hepatitis B virus-associated cirrhosis, a liver mass was detected on abdominal CT. Macroscopically, the resected tumor wa...

Lymphoepithelioma-like carcinoma (LELC) of the breast is an exceedingly rare variant of mammary cancer. To our knowledge, only twenty - one cases have been reported in the literature. Diagnosis of this type of mammary carcinoma may be challenging, owing to its rarity and the histopathological similarity to common inflammatory and malignant lesions of the breast mainly granulomatous mastitis, me...

metaplastic carcinoma is a rare form of breast cancer and is a generic term for breast carcinoma of ductal type in which the predominant component of the neoplasm has an appearance other than epithelial glandular structures.we report a case of this rare tumor in as 57-year-old psot- menopausal woman

The stem cell factor (SCF) receptor CD117 (c-kit), is widely used for identification of hematopoietic stem cells and cancer stem cells. Moreover, CD117 expression in carcinoma cells indicates a poor prognosis in a variety of cancers. However the potential expression in tumor microenvironment and the biological and clinical impact are currently not reported. The expression of CD117 was immunohis...

Primary Carcinoma of the liver is a rare disease in Iran like most parts of the world.  The incidence of this disease is about 2-8 times more in male than female but in Iran the ratio is almost equal between the two sexes.  The highest incidence in this country is in the age groups of 41-50 and 51-60. This seems to be in a lower age group in comparison to the United Slates as well as in other...

Salivary duct carcinoma (SDC) is a prototypic aggressive salivary gland carcinoma. Our aim is to determine the prevalence of histologic variants (micropapillary, basal-like) and androgen receptor (AR) expression in a large multi-institutional series of SDC. AR status was determined by immunohistochemistry (IHC). Most SDCs were characterized by an apocrine phenotype and AR expression. Cases with...

thelioma-like gastric carcinoma that presented as a flat depressed lesion and was treated by complete en-bloc resection using endoscopic submucosal dissection (ESD). A 73-year-old manwas referred to the department of internal medicine because of an incidental finding suspicious of early gastric cancer. The patient’s medical history and laboratory test results were unremarkable. Gastroscopy reve...