Bisadduct isomers of a H(2)@C(60) derivative with nitroxide addends have been synthesized, isolated and characterized. The (1)H NMRs of endohedral H(2) of the major isomers show well-separated chemical shifts, which could be useful for structural assignment and identification of the purity of the C(60) bisadduct isomers.

We compared the differential effects of positional isomers of acetylsalicylic acid (o-ASA, m-ASA, and p-ASA) on cyclooxygenase (COX) inhibition, gastric prostaglandin E2 (PGE2), malondialdehyde, tumor necrosis factor-alpha (TNF-α) levels, superoxide dismutase (SOD) activity, human adenocarcinoma colon cancer cell growth inhibition, cell proliferation, apoptosis, and cell-cycle progression. We a...

Positional isomers of decenoic, dodecenoic, and tetradecenoic acids of human adipose tissue have been separated by gas-liquid chromatography and their amounts determined by oxidative cleavage. The following acids have been shown to be present: 7-decenoic, 8-decenoic, 9-decenoic, 7-, 8-, and 9-dodecenoic, and 7-, 8-, 9-, and 11-tetradecenoic acids. Among all isomers of the even-numbered acids fr...

Static quadrupole moments (0) of 8+ isomers in 88 90Zr and the 2' + isomer in 9'Zr, as well as 0 ratios of 8+ isomers in Mo, have been measured with the time-differential perturbedangular-distribution technique. The isomers were excited by pulsed heavy-ion beams and recoil implanted into single crystals of Zr in which their quadrupole precession was observed. Our results, the first such data fo...

A chiral high pressure liquid chromatography method was developed to measure the separate isomers of prilocaine in plasma after administration of the racemate. The concentrations of the isomers in six patients were similar (S(+)/R(-) = 1.06 (SD 0.06)) after brachial plexus block with 1.5% (RS)-prilocaine hydrochloride 35 ml, suggesting that a higher systemic safety margin may not be achieved by...

Domains of different surface reconstruction-negatively or positively buckled isomers-have been previously observed on highly n-doped Si(111)-2 × 1 surfaces by angle-resolved ultraviolet photoemission spectroscopy and scanning tunneling microscopy/spectroscopy. At low temperature, separate domains of the two isomer types are apparent in the data. It was argued in the previous work that the negat...

The relationships between the adipose tissue concentrations of 19 geometric and positional fatty acid isomers and 10 cardiovascular disease risk factors were determined in 76 free-living adult males. The percentages for trans isomers (total mean +/- SD 4.14 +/- 0.97%) and cis isomers (total mean +/- SD 2.91 +/- 0.34%) in adipose tissue generally agreed with dietary estimates based on the consum...