Abstract The lipid-based colloidal carriers, such as nanostructured lipid carriers (NLCs), solid nanoparticles (SLNs), nanocapsules, liposomes, and microemulsion, are the latest significant entrants in development of drug delivery systems owing to their myriad advantages. NLCs second-generation SLNs having unstructured matrix, have high loading, provide long-term stability comparison other syst...