نتایج جستجو برای: lipid based nanoparticles

تعداد نتایج: 3164302  

2014
Ana-Maria MANEA Corina ANDRONESCU Aurelia MEGHEA Ana-Maria Manea Corina Andronescu Aurelia Meghea

The aim of this study was to synthesize by high shear homogenization method and to characterize new solid lipid nanoparticles loaded with green tea extract, nanoparticles which show high antioxidant activity. In this respect, cetyl palmitate and glyceryl stearate were used as solid lipids in combination with two nonionic surfactants, Tween20 and Tween80 and an ionic surfactant as lecithin. The ...

2016
Olga Panyuta Viktoriya Belava Svitlana Fomaidi Olena Kalinichenko Mykola Volkogon Nataliya Taran

The paper presents research data of lipid peroxidation and lectin activity in wheat seedlings at seed treatment with solution of metal nanoparticles (Zn, Ag, Fe, Mn, Cu) and sole solution of copper nanoparticles under the high pathogen infection background of Pseudocercosporella herpotrichoides (Fron) Deighton (synonym: Oculimacula yallundae (Wallwork & Sponer) Crous & W. Gams). It was shown th...

Journal: :Physical chemistry chemical physics : PCCP 2013
Edroaldo Lummertz da Rocha Giovanni Finoto Caramori Carlos Renato Rambo

An enhanced understanding about the interactions between nanomaterials and cell membranes may have important implications for biomedical applications. In this work, coarse-grained molecular dynamics simulations of gold nanoparticles interacting with lipid bilayers were performed to evaluate the effect of hydrophobicity, charge density and ligand length on lipid bilayers. The simulations accompl...

Journal: :ACS nano 2013
Isaac Salib Xin Yong Emily J Crabb Nicholas M Moellers Gerald T McFarlin Olga Kuksenok Anna C Balazs

Using dissipative particle dynamics (DPD) simulations, we model the interaction between nanoscopic lipid vesicles and Janus nanoparticles in the presence of an imposed flow. Both the vesicle and Janus nanoparticles are localized on a hydrophilic substrate and immersed in a hydrophilic solution. The fluid-driven vesicle successfully picks up Janus particles on the substrate and transports these ...

2010
M. A. García V. Bouzas S. Veintemillas P. Morales M. García-Hernández R. Alexandrescu I. Morjan P. Gasco

Abstract. We report on the magnetic characterization of Fe oxide nanoparticles by laser pyrolysis and the relationship between the preparation conditions and the magnetic response. It is shown that controlling the preparation conditions during the pyrolisis allows tuning the nanoparticles morphology and structure and consequently the magnetic properties of the nanoparticles. The nanoparticles a...

2016
K. Ognik E. Cholewińska A. Czech K. Kozłowski Ł. Wlazło R. Szlązak K. Tutaj

The aim of the study was to analyze how per os application of hydrocolloids of silver nanoparticles (22 nm) and lipid-coated silver nanoparticles (5 nm) affect the immune, redox, and lipid status of the blood of broiler chickens. The experiment was conducted on 60 chickens. The first group was the control (Group C). The chickens in Group II received a silver nanoparticle hydrocolloid (Ag-nano) ...

Journal: :Advanced drug delivery reviews 2012
Dan Peer

Lipid-based nanoparticles (LNPs) such as liposomes, micelles, and hybrid systems (e.g. lipid-polymer) are prominent delivery vehicles that already made an impact on the lives of millions around the globe. A common denominator of all these LNP-based platforms is to deliver drugs into specific tissues or cells in a pathological setting with minimal adverse effects on bystander cells. All these pl...

2013
Andrew D. Miller

Today, researchers are constantly developing new nanomaterials, nanodevices, and nanoparticles to meet unmet needs in the delivery of therapeutic agents and imaging agents for cancer therapy and diagnosis, respectively. Of particular interest here are lipid-based nanoparticles (LNPs) that are genuine particles (approximately 100 nm in dimension) assembled from varieties of lipid and other chemi...

Journal: :Molecular pharmacology 2008
Jun-Jie Yin Fang Lao Jie Meng Peter P Fu Yuliang Zhao Gengmei Xing Xueyun Gao Baoyun Sun Paul C Wang Chunying Chen Xing-Jie Liang

Intraperitoneal injection of [Gd@C82(OH)22]n nanoparticles decreased activities of enzymes associated with the metabolism of reactive oxygen species (ROS) in the tumor-bearing mice. Several physiologically relevant ROS were directly scavenged by nanoparticles, and lipid peroxidation was inhibited in this study. [Gd@C82(OH)22]n nanoparticles significantly reduced the electron spin resonance (ESR...

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