BACKGROUND We conducted a study in order to determine the usefulness and diagnostic value of International Autoimmune Hepatitis Group (IAHG) score in non-autoimmune hepatitis (AIH) hepatic disorders as well as in AIH/overlap syndromes and in cases with coexistence of AIH and other liver diseases. METHODS We applied the IAHG score in 423 patients with liver diseases excluding patients with AIH...

Vascular disorders of the liver, although affecting less than 5/10,000 patients, collectively account for a number of rare conditions that represent an important health problem worldwide in the field of liver diseases. A common characteristic of most of these disorders is that they can cause non-cirrhotic portal hypertension with an ensuing high morbidity and mortality. In addition, special rel...

non-alcoholic fatty liver disease (nafld) is the leading cause of chronic liver disease in the united states and other industrialized countries, and the reported prevalence in the developing countries is also rather high. this disease is associated with a high rate of morbidity and mortality and damage to the other organs. the cardiovascular system is, perhaps, the most vulnerable organ to nafl...

Background: Type-2 diabetes is a risk factor for progressive non-alcoholic fatty liver disease and the majority of diabetic patients have blood lipid disorders, so they take statin drugs. Statins have the adverse effects such as liver dysfunction and increase in liver enzymes. The purpose of this study was to compare the liver enzymes in type 2 diabetic patients who are user and non-user of sta...

background: cynara scolymus and cichorium intybus are popular herbal remedy in folk medicine for liver disorders. although many experimental studies carried out, scientifically reliable data needed to verify minimum effective dosage and efficacy of these medicinal plants. objective: in present investigation, the effects of c. scolymus leaf and c. intybus root extracts at different doses were te...

The thrombelastogram is a method used to monitor clotting dynamics. Thrombelastography (TE) has been used to guide therapy of coagulation disorders mostly in cardiac surgery but also in liver surgery. TE is a useful tool for perioperative management of patients at risk for coagulopathy. There are several reports describing the use of the thrombelastogram in patients undergoing orthotopic liver ...

Vanishing Bile Duct Syndrome (VBDS) refers to the group of acquired disorders associated with progressive destruction and disappearance of the intrahepatic bile ducts and, ultimately, cholestasis. This is a final common pathologic pathway, resulting from multiple etiologies including autoimmune disorders, medications, genetic abnormalities, infectious diseases, and neoplastic disorders.1 Variou...

INTRODUCTION Hepatic disorders in infancy and childhood continue to pose problems in regard to their management. Even though the aetiological factors are many and some of them ill-understood today, the manifestation is the same that of hepatic insufficiency. Since liver performs many functions of the body some understood well, some not so well and others not at all—a drug that would help in kee...