BACKGROUND Leptomeningeal metastasis (LM) is recently on the rise as one of important clinical issues in the management of metastatic breast cancer (MBC). Clinical research on salvage intrathecal chemotherapy after failure of first-line treatment for MBC patients with LM has rarely been reported. CASE REPORT We report the case of a breast cancer patient with LM who showed durable response to ...

Neonates suffer unduly from infections and also respond suboptimally to most commonly used vaccines. However, a CD8 T cell response can be elicited in neonates if the Ag is introduced into the cytoplasm of APCs. Listeria monocytogenes (Lm) targets the cytoplasm of APC and is a strong CD8 and CD4 Th1-promoting vaccine vehicle in adult mice. We hypothesized that an attenuated strain of Lm would b...

The larynx of Xenopus laevis is a sexually differentiated vocal organ in which male muscle is entirely fast twitch and expresses high levels of a fast twitch myosin heavy chain gene, LM. Female muscle, however, is mostly slow twitch and expresses little LM. Androgen is unable to induce expression of LM until after metamorphosis is complete. The expression of LM during metamorphic and early post...

OBJECTIVE To describe the frequency of lymphocytic meningitis(LM) concomitant with mumps, before and after the mumps mass immunization campaign in 1997. METHOD Demographic, clinical and cerebrospinal fluid(CSF) information was collected from the chart of all patients aged from 2 to 59 months, whose CSF exam was performed at the CSF Lab/FJS, between 1989 and 2001. LM was defined as pleocytosis...

We address the issue of data sparseness problem in language model (LM). Using class LM is one way to avoid this problem. In class LM, infrequent words are supported by more frequent words in the same class. This paper investigates a class LM based on LSA. A word-document matrix is usually used to represent a corpus in LSA framework. However, this matrix ignores word order in the sentence. We pr...

Background: A few reports confirm the ability of Helicobacter pylori to form biofilm. However, conclusive data do not exist concerning the factors that favor this ability.Objectives: Evaluation of the factors associated with the biofilm formation ability of H. pylori including bacterial, physical and chemical, and environmental factors was the research’s aim.Materials and Methods: H...

In recent work I have tried to spell out a Post Walrasian approach to macroeconomics (Colander, 1995a) and to translate that Post Walrasian vision into the aggregate supply/aggregate demand framework (Colander, 1995b). In this paper I continue that work and begin to relate the Post Walrasian vision to the standard IS/LM analysis. The paper is not about high theory; instead it is about the pedag...