objective: parkia biglobossa stem bark decoction is a popular medicinal plant preparation used as calming agent for tensed patients in traditional medicine. the aim of this study was to evaluate the effects of aqueous stem bark extract of parkia biglobossa (aepb) and its active fraction aepbf3 on anxiety, spontaneous alternation behavior, and locomotor activity. the open field apparatus was use...

background and objectives cannabinoids which are active compounds of marijuana show some pharmacological effects similar to the opioids. there are also functional interactions between both cannabinoid and opioid systems. in this study we investigated the role of cannabinoid receptors in central amygdala and its interaction with opioid system.   methods in the present study, we investigated the ...

A study of the elderly living in the community and in institutional care in the Leeds Metropolitan District is outlined. Four populations of persons aged 65 and over were examined: those living in their own homes; in sheltered housing; in social services aged persons' hostels (Part III accommodation); and in hospitals. Findings on one key concept--coping ability--are discussed. Those living in ...

Locomotor disorders are very common in the equine clinic, which may be partly due to the different types of activities horses develop. Osteoarthritis (OA), commonly known as degenerative joint disease, presents an considerable role in the series of disorders of the musculoskeletal system and may be associated with other problems such as navicular syndrome, periostitis or osteochondrosis. This a...

Spontaneous rhythmic motor output of crayfish thoracic ganglia consists of bursts of activity in antagonistic leg motor neurons (MNs), alternating with a rather slow cycle period (typically > or = 20 s). The most common pattern (77% of preparations) consists of long coxal promotor bursts, the duration of which was correlated strongly with cycle period, and relatively short remotor bursts indepe...

Rhythm generation in neuronal networks relies on synaptic interactions and pacemaker properties. Little is known about the contribution of the latter mechanisms to the integrated network activity underlying locomotion in mammals. We tested the hypothesis that the persistent sodium current (I(NaP)) is critical in generating locomotion in neonatal rodents using both slice and isolated spinal cord...

In lampreys as in other vertebrates, the reticulospinal (RS) system relays inputs from the mesencephalic locomotor region (MLR) to the spinal locomotor networks. Semi-intact preparations of larval sea lamprey were used to determine the relative contribution of the middle (MRRN) and the posterior (PRRN) rhombencephalic reticular nuclei to swimming controlled by the MLR. Intracellular recordings ...

Almost every day, horses with unspecified lameness and locomotor disorders are being examined in numerous equine orthopaedic surgeries all over Germany. "In most cases, young horses with particularly strong movements are concerned that perfectly reflect today's breeding goals for sport horses", reports FEI veterinarian Dr. Mark Kaminski. The veterinary specialist in equine orthopaedics at the e...

R HEUMATIC complaints are among the commonest of the certificated causes of sickness absence from work (Report of Ministry of Pensions 1966). Such painful disorders of the locomotor system are common in general practice: in the study by the College of General Practitioners and the Registrar General's Office, the prevalence rate of this group of conditions was second only to that for nasopharyng...

There are numerous causes that can affect the functioning of the human locomotor system, leading to the appearance of joint disorders in the lower limb and generating atypical gait patterns. The importance of research and development in assistance technologies to compensate pathological gait have been recognised since the beginning of the twentieth century and numerous challenges still lie ahea...