Background and Aim: Captopril is an oral angiotensin-converting-enzyme (ACE) inhibitor extensively used in the treatment of hypertension and heart failure. ACE has been suggested to function in bone cells and might therefore impact orthodontic tooth movement (OTM). Considering the controversy surrounding the effects of ACE and its inhibitors on osseous tissues, we aimed to evaluate the effect o...

'E now know, that, in the long bones of the human body, a portion of the bony cylinder may be deprived of the living principle; and that, in fuch cafes, nature gradually feparates the living from the dead part. While this feparation is taking place, a new cylinder is formed by an effufion of bony matter, fo as to inclofe the old bone, as it were, in a cafe ; and the new bone conneding itfelf wi...

Although there is much data available on mammalian long-bone allometry, a theory explaining these data is still lacking. We show that bending and axial compression are the relevant loading modes and elucidate why the elastic similarity model failed to explain the experimental data. Our analysis provides scaling relations connecting bone diameter and length to the axial and transverse components...

There is a need to explore novel methods of assessing bone health in sick preterm infants. This study of the speed of sound in the long bones of newborn term and preterm infants shows that, in this population, this technique is not site specific and has a high degree of interobserver and intraobserver precision. The speed of sound in newborn infants is primarily dependent on gestation rather th...

Estimation of sex when investigating subadult skeletal remains is largely problematic because of unreliable and inaccurate results. Despite the limitations encountered with skeletal material, the medical literature clearly demonstrates differences between males and females in utero that persist through life. The current study investigates sexual dimorphism in the long bones of the humerus and f...

Infected nonunion is one of the most challenging orthopaedic complications to manage. There is considerable morbidity associated with infected nonunion. There is significant impact on the life of the patient; social, financial, physical, and mental. Infected nonunion may be a limb-threatening complication. Significant progress has been made in the management of infected nonunion in the last dec...

Recently, an electrophysical approach has been applied to the study of the long bone in order that a more complete understanding of its growth and structural integrity become available. Experimental studies have indicated that weak electric fields may be detected in living bone, in vivo, as the result of externally applied loads, normal weight bearing and pulsatile blood flow. In addition, phys...

Florid reactive periostitis is a pronounced periosteal reaction, usually affecting the hands and feet, for which there is no obvious cause. It is rare in children and in long bones. We report an unusual case of florid reactive periostitis in a ten-year-old girl that involved both bones of the forearm. The lesion resolved over a period of one year, leaving a residual exostosis. She developed a p...

Note Ollier disease was first described by Louis Ollier, a French surgeon in early 1800s. The disorder is characterized by the presence of at least three enchondromas. Ollier disease manifests early in childhood and affects both sexes equally. Lesions are distributed unilaterally. In Ollier disease, enchondromas form in the medulla of mainly long bones and it is now clear that Ollier disease is...