Background: When searching for reliable and specific markers for certain psychiatric diseases, preliminary investigations of the sleep EEG’s microstructure point to the view that the delta/beta correlation coefficients during NREM sleep appear increased in depressives, but not in schizophrenics. Therefore, this parameter could be hypothesized to be a marker of depression. On the other hand, sub...

The current paper focuses on a relatively new and promising area of the study of EEG transformations during brain information processing based on the reduction of the signal to the discrete quasi-stationary segment sequences which may reflect individual brain microstates or discrete operations. In this framework, the complex brain functions require integration of several operations throughout t...

BACKGROUND Abrupt cessation of alcohol intake causes habituated drinkers to experience symptoms of alcohol withdrawal syndrome (AWS). OBJECTIVE To determine the effect of the gamma-aminobutyric acid (GABA)-B agonist baclofen on the course of acute symptomatic AWS. DESIGN Prospective, randomized, double-blind, placebo-controlled clinical study. SETTING Two tertiary-care hospitals in Duluth...