It is well known that ionizing radiation is currently a very important way to create genetic variability that is not exists in nature or that is not available to the breeder (Ahloowalia & Maluszynski, 2001; Lemus et al., 2002). Therefore, there are many papers aimed to determine the best radiation dose to applied in plant breeding work. As a result it has been defined intervals gamma radiation ...

Investigation of mutational specificity at low doses has generally not been possible since the number of induced mutants may be similar or significantly lower than the spontaneous background. The use of a low-dose fractionated exposure protocol in TK6 human lymphoblasts results in an incremental accumulation of mutants induced by individual 20 cGy gamma-ray exposures. Therefore, the frequency o...

background and objective: professional radiation workers are occupationally exposed to long-term low levels of ionizing radiation. occupational health hazards from radiation exposure, in a large occupational segment of the population, are of special concern. biological dosimetry can be performed in addition to physical dosimetry with the aim of individual dose assessment and biological effects....

Studying of the effects of low doses of γ-irradiation is a crucial issue in different areas of interest, from environmental safety and industrial monitoring to aerospace and medicine. The goal of this work is to identify changes of lifespan and expression stress-sensitive genes in Drosophila melanogaster, exposed to low doses of γ-irradiation (5-40 cGy) on the imaginal stage of development. Alt...

The concept of DNA "repair centers" and the meaning of radiation-induced foci (RIF) in human cells have remained controversial. RIFs are characterized by the local recruitment of DNA damage sensing proteins such as p53 binding protein (53BP1). Here, we provide strong evidence for the existence of repair centers. We used live imaging and mathematical fitting of RIF kinetics to show that RIF indu...

background: the fatal effect of ionizing radiation on cells depends on linear energy transfer (let) level. the distribution of ionizing radiation is sparse and homogeneous for low let radiations such as x or γ, but it is dense and concentrated for high let radiation such as heavy-ions radiation. material and methods: chinese hamster ovary cells (cho-k1) were exposed to 4 gy fe-ion 2000 kev/m. ...

The effects of combined photodynamic therapy (PDT) and ionizing radiation are studied in a human glioma spheroid model. The degree of interaction between the two modalities depends in a complex manner on factors such as PDT irradiation fluence, fluence rate and dose of ionizing radiation. It is shown that gamma radiation and PDT interact in a synergistic manner only if both light fluence and ga...

The space environment consists mainly of high-energy charged particles, such as protons, electrons and heavy ions. They are originating from several sources including galactic cosmic radiation, solar flares and van Allen belts. High energy electromagnetic radiation and neutrons have also been measured on spacecraft. Although shielding can reduce the effect of space radiation it cannot be elimin...