Rare variant association studies are gaining importance in human genetic research with the increasing availability of exome/genome sequence data. One important test of association between a target set of rare variants (RVs) and a given phenotype is the sequence kernel association test (SKAT). Assignment of weights reflecting the hypothesized contribution of the RVs to the trait variance is embe...

the present universities are deploying IPv6 campus network actively, protecting the existing investment and equipment need a gradual transition process safely. In order to achieve the fast communication between IPv4 /IPv6 hybrid network, a BRT three-dimensional interchange system is proposed. By introducing kinds of technologies and communication solutions in this paper, the system is realized ...

[1] We assess the importance of distant pollution sources on the marine background by combining measurements of carbon monoxide (CO) and ozone (O3) with model simulations from the GEOS-CHEM chemical transport model and two types of back trajectories. Measurements were made over a complete annual cycle from March 2001 to May 2002 at Cheeka Peak Observatory (CPO) in Washington State. Data from an...

Background: The role of locoregional radiotherapy (LRT) the nasopharynx and neck in patients with metastatic nasopharyngeal carcinoma (M-NPC) remains unclear. present meta-analysis aimed to compare efficacy chemotherapy (CT) plus LRT CT alone M-NPC patients.

Light Rail Transit (LRT), integrated with river transportation as a unique city and tourist attraction, is important in supporting smart cities. This study aims to assess the possibilities of users who use LRT an advanced mode its infrastructure. research quantitative descriptive approach. Primary data obtained from survey movement outside Palembang City has potential continue their journey usi...

Since the 1970s great progress has been made to develop transit systems which provide service considerably better than buses can offer in mixed traffic, but which require significantly lower investment than metro systems with exclusive ways. This “semirapid transit” category of modes, using mostly partially separated ways, has been introduced extensively in medium-sized cities, as well as suppl...

Inference of variance components in linear mixed effect models (LMEs) is not always straightforward. I introduce and describe a flexible SAS ® macro (%COVTEST) that uses the likelihood ratio test (LRT) to test covariance parameters in LMEs by means of the parametric bootstrap. Users must supply the null and alternative models (as macro strings), and a data set name. The macro calculates the obs...

Readers may be surprised by the recent editorial of Dr. Rosenberg, ‘Current evidence is not in support of lipid rescue therapy in local anaesthetic systemic toxicity’. Lipid rescue therapy (LRT) is widely accepted and recommended for treating local anaesthetic systemic toxicity (LAST) but Dr. Rosenberg purports that the efficacy and safety data are insufficient to warrant its use for this indic...