Nodal activity in the left lateral plate mesoderm (LPM) is required to activate left-sided Nodal signaling in the epithalamic region of the zebrafish forebrain. Epithalamic Nodal signaling subsequently determines the laterality of neuroanatomical asymmetries. We show that overactivation of Wnt/Axin1/beta-catenin signaling during late gastrulation leads to bilateral epithalamic expression of Nod...

The problem of constructing model reference adaptive H∞ control for flexible arms is considered in this manuscript. Control schemes of flexible arms are mixed parameter systems composed of distributed parameter systems of hyperbolic type (flexible arms) and lumped parameter systems (motor control systems). Owing to infinite dimensional modes of distributed parameter systems, control of those co...

The continuous-time (CT) domain in Ptolemy II aims to help the design and simulation of systems that can be modeled using ordinary differential equations (ODEs). ODEs are often used to model analog circuits, plant dynamics in control systems, lumped-parameter mechanical systems, lumpedparameter heat flows and many other physical systems. Let’s start with an example. Consider a second order diff...

This paper deals with the model predictive control of processes. The new step is the use of a distributed parameter system instead of a lumped parameter system. The internal model control structure is also used to solve the trajectory tracking problem. The internal model is obtained from the linearization of the initial set of nonlinear partial differential equations about the desired trajector...

The horn loudspeaker suffers from producing high distortions. Based on an physical model an equivalent lumped parameter circuit is determined for a horn loaded compression driver. From the nonlinear differential equation of this circuit, a compensation algorithm is implemented on a Digital Signal Processor (DSP) for reducing nonlinear distortion caused by the behaviour of air. Test results are ...

The objective of this lecture is to review the basic building blocks of lumped parameter rotational mechanical systems and to build the foundations that will enable you to model more complex dynamic systems consisting of translation and rotational elements. Corresponding to the translational elements mass, spring and damper, are the rotational inertia, rotational spring and rotational damper, r...

This paper presents a wireless diaphragm actuator and focuses on a lumped parameter grey-box model capable of simulating actuation displacement. Here, modelling aims to provide further insight into this smart material actuator and help facilitate design into new implantable applications. Model parameters were calibrated to a prototype actuator using experimental data and a genetic algorithm opt...