نتایج جستجو برای: lynch syndrome
تعداد نتایج: 623651 فیلتر نتایج به سال:
Primary intimal sarcomas are uncommon and highly lethal tumors arising in the mesenchymal tissue of great arteries [1-3]. In this setting, primary Pulmonary Artery Sarcomas (PAS) are often misdiagnosed with a poor prognosis due to their extreme aggressiveness [1-3]. Conversely, Lynch Syndrome is an inherited disorder with an increased risk of developing colorectal cancer, and a well defined spe...
Background The molecular diagnosis of hereditary non-polyposis colorectal cancer (HNPCC) or Lynch-Syndrome is the detection of a pathogenic germline mutation in one of the DNA mismatch repair (MMR) genes. However, in ~10-20% of cases suspected of Lynch-syndrome no disease-causing mechanism can be detected. Genomic rearrangements such as gene-flanking deletions, inversions, duplications, or tran...
Diagnosis and treatment of epithelial ovarian cancer is challenging due to the poor understanding of the pathogenesis of the disease. Our aim was to investigate epigenetic mechanisms in ovarian tumorigenesis and, especially, whether tumors with different histological subtypes or hereditary background (Lynch syndrome) exhibit differential susceptibility to epigenetic inactivation of growth regul...
Introduction Myocardial involvement in polymyositis has been increasingly recognized since it was first reported by Oppenheim (1899). Cardiac manifestations include congestive cardiac failure (Lynch, 1971; Bohan et al., 1977; Denbow et al., 1979), pericarditis (Lynch, 1971), atrioventricular and bundle branch block (Lynch, 1971, Schaumburg, Nielsen and Yurchak, 1971; Henderson et al., 1980) and...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید