The Malassezia fungi are responsible for various human skin disorders including dandruff and seborrheic dermatitis. Of the Malassezia fungi, Malassezia globosa (M. globosa) is one of the most common in human scalp. The completed genome sequence of M. globosa contains four putative cytochrome P450 genes. To determine the roles of Malassezia P450 enzymes in the biosynthesis of ergosterol, we isol...

The mortality associated with invasive fungal infections remains high with that involving rare yeast pathogens other than Candida being no exception. This is in part due to the severe underlying conditions typically predisposing patients to these healthcare-related infections (most often severe neutropenia in patients with haematological malignancies), and in part due to the often challenging i...

The frequencies of isolation and population sizes of Malassezia spp. on skin and at mucosal sites in 16 cats with diabetes mellitus, 20 cats with hyperthyroidism and 8 cats with neoplasia did not vary significantly from those of healthy cats when measured with the use of contact plates and a swab technique. M. pachydermatis was isolated from nine sites in one cat with feline paraneoplastic alop...

Although the fungal microbiome in human skin mainly comprises lipophilic yeasts, including Malassezia species, these microorganisms can cause various dermatitis conditions, pityriasis versicolor, seborrheic dermatitis, folliculitis, and atopic depending on host condition. Both globosa restricta are major species implicated Malassezia-related dermatitis. However, pathogenicity of has not been re...

The objective of this study was to determine the presence of different species of the genus Malassezia in the healthy external auditory canal of wild felids maintained in captivity. One hundred and thirty-two adult animals (264 samples of cerumen), 77 males (58.3%) and 55 females (41.7%), were studied: large felids (55 animals) - 26 lions (Panthera leo), 13 tigers (Panthera tigris), 6 leopards ...

Numerous organisms are have zoonotic potential; many are devastating, horrible diseases (Table Z at end of notes). However, some of the organisms that veterinary practitioners encounter on a daily basis (Staphylococcus, Malassezia, Pseudomonas, and Microsorium canis) have recently demonstrated an increasing potential to cross the species barrier that most of us assumed protected ourselves, staf...

TO THE EDITOR Seborrheic dermatitis (SD) is a chronic inflammatory disease that compromises skin areas rich in sebaceous glands, such as the face, scalp, and upper trunk. The condition is frequently observed in acquired immune deficiency syndrome patients (30–85% compared with 3–5% of immunocompetent adults). Its appearance is considered to be an early marker of the evolutionary trend of HIV in...

The aim of this study was to characterize the mycobiome associated with oral squamous-cell carcinoma (OSCC). DNA was extracted from 52 tissue biopsies (cases: 25 OSCC; controls: 27 intra-oral fibro-epithelial polyps [FEP]) and sequenced for the fungal internal transcribed spacer 2 region using Illumina™ 2 x300bp chemistry. Merged reads were classified to species level using a BLASTN-algorithm w...

Fifty-two strains of the yeast species Malassezia pachydermatis were analysed by multilocus enzyme electrophoresis. M. pachydermatis appeared to be genetically heterogeneous. A total of 27 electrophoretic types were identified that could be divided into five distinct groups with different host specificities. The diversity revealed by this electrophoretic method matched remarkably well the repor...