PURPOSE In Iranian traditional medicine there is a belief that camphor is a suppressor of sexual activity. Based on this idea and since there are few studies on this issue, we evaluated the effect of camphor on histopathological changes of reproductive system in young male mice of balb/c racial type. MATERIALS AND METHODS Thirty-six premature male balb/c mice, were divided into 3 paired group...

This study aimed to characterize the effect of apigenin on the reproductive system in male mice. Adult male mice were treated with intraperitoneal injection of apigenin at the dose levels of 5, 10, 15, 20 and 25 mg/kg.bw, 0.05% DMSO and 0.9% normal saline daily for seven days. Then, testis and epididymis sperms in sperm motility, sperm morphology, the percentages of ploidy cells and seminiferou...

Problem statement: Urtica pilulifera L. (Urticaceae), has long been used for the treatment of various aliments including diabetes. Diabetes is a metabolic disorder characterized by hyperglycemia which has a deleterious effect on all systems including reproductive system of animals. Therefore, the current study was designed to investigate the effects of Urtica pilulifera on the reproductive syst...

Vitamin E (毩-tocopherol) is fat soluble organic compound and commonly present in the cell membranes. This vitamin has the strong antioxidant properties and inhibits the lipid peroxidation created by the free hydroxyl and superoxide radicals. This vitamin protects the cell membrane of sperm cell from damages of ROS. In vitro studies have proved that the use of vitamin E improves the motility and...

OBJECTIVE To evaluate effects of cypermethrin on the testis histology and testosterone, LH and FSH in adult male Sprague-Dawley rats. METHODS The intact adult male rats were randomly divided into five groups and were treated with cypermethrin at doses of 0, 7.5, 15, 30, or 60 mg/kg per day by oral gavage for 15-days. After the treatments, serum was collected for hormone assays. The testes, ep...

The preservation of reproductive health of the population is an important factor of demographic policy of the state. According to some authors from 14 to 30% of couples of reproductive age suffer from infertility, malefactor in such marriages is detected in more than half of the cases. As you know, in recent years there has been a significant deterioration in the main indicators of reproductive...

Globally Harmonized System defines Reproductive Toxicity as “an adverse effects (of chemicals) on sexual function and fertility in adult males and females, as well as developmental toxicity in the offspring.” Several toxicity assessment studies have been performed taking into account the action of toxicants on reproductive activity. Testis is the main organ of male reproductive system and sperm...

Male reproductive disease are the diseases that affect male system. There is rise in number of patients infertility and increasing system abnormalities such as cryptorchidism, germ cell tumor from all over world. In recent years, cases have increased. They principally found to be associated with life style environment factors. Various Assisted Reproductive Technologies like IVF, IUI been introd...

Hypospadias is the most common anomaly in the male genital tract with an incidence of 0.8-8.2 per 1000 live male births. Routinely, hypospadias cases are repaired after one year of age, and it is recommended that a child with hypospadias not to be circumcised until hypospadias repair is completed. This study was conducted to determine whether or not circumcision prior to hypospadias repair incr...

Fertility in the male is dependent on the proper production of sperm cells. This process, called spermatogenesis is very complex and involves the synchronization of numerous factors. The presence of pro-inflammatory cytokines, tumor necrosis factor-alpha (TNF-α), interleukin-1 alpha (IL-1 α) and interleukin 1 beta (IL-1 β) cytokines in the male reproductive tract (testis, epididymis and sperm) ...