CONTEXT The diagnosis of primary melanoma is easily confirmed after histological analysis of the lesion, whereas it is rarely diagnosed when the patient even has distant metastases. DESIGN Case report CASE REPORT Malignant melanoma is responsible for about 1% of all deaths caused by cancer in the USA and only 3% of all malignant skin diseases. Malignant melanoma is a rare disease, although ...

We report a case of primary malignant melanoma of the urinary bladder. Exclusion of other sites of melanoma confirmed the primary character of the tumor, and careful histologic examination proved it to be malignant melanoma. Six previously reported cases of bladder melanoma are reviewed. Therapy and prognosis are discussed.

About half of all patients with malignant melanoma have cardiac metastases. Histological confirmation antemortem of a secondary malignant melanoma of the heart is difficult. The diagnosis of a secondary melanoma in the right atrium was confirmed by transvenous biopsy in a 46 year old woman who had had a melanoma excised from her right leg two years before.