OBJECTIVE The authors suggest criteria for a range of narrow to broad phenotypes of bipolar disorder in children, differentiated according to the characteristics of the manic or hypomanic episodes, and present methods for validation of the criteria. METHOD Relevant literature describing bipolar disorder in both children and adults was reviewed critically, and the input of experts was sought. ...

The present study investigated how symptoms of mania—associated with heightened and persistent positive emotion—influence emotion experience and perception during distressing social interactions, whereby the experience of heightened positive emotion may not be socially adaptive. Specifically, mania symptoms were assessed via a validated self-report measure, and used to predict emotion experienc...

Mania in late life is a serious disorder that demands specialist assessment and management. However, it is greatly under-researched, with only a paucity of studies specifically analysing older populations. The mainstay of the old age psychiatry workload will inevitably be concerned with assessing and managing dementia and depression, but the steady rise in the aging population with longer survi...

A case of parkinson's disease starting 7 yrs. ago in 1993 with 2 episodes of mania is presented. The 1st episode (1993) was of 1-1/2 months duration, when early parkinsons symptoms had already set in. This was treated with anti-psychotic medications for a month, the picture was complicated with stroke and post-stroke sequlae for 5-6 months, where anti-psychotics were continued. He developed dys...

Researchers and clinicians have long noted the overlap among features and high comorbidity of bipolar disorder and borderline personality disorder. The shared features of impulsivity and labile mood in both disorders make them challenging to distinguish. We tested the hypothesis that variables related to goal dysregulation would be uniquely related to risk for mania, while emotion-relevant impu...

Humans have the ability to mentally time travel through past, present, and future. But can a disruption in emotion characteristic of emotional disorders cause this ability to unwind, leaving people "stuck" in the present emotional moment? Two studies are presented that examine emotional time-perspective in a disorder (mania) characterized by present-oriented tendencies, including impulsivity an...

Until now, in various parts of the world, no consensus has been reached with regard to the treatment of acute mania. Controlled clinical trials have at last provided irrefutable evidence for the effectiveness of lithium, which had long been used alone, as well as that of divalproate or its derivatives and, to a lesser extent, carbamazepine (1). In Europe, haloperidol is still the reference comp...

T h e proposal to divide manic depressive illness into separate bipolar (alternating mania and depression) and unipolar (recurrent depression or recurrent mania) psychoses was first brought-forward by Leonhard (1959), but it was Angst (1966) who first produced convincing evidence in support of the divison. Perris (1968) was able to show that bipolar illness started on average of fifteen years e...

Bipolar Disorder (BD) is a neuropsychiatric disorder characterized by symptoms ranging from a hyperactive manic state to depression, with periods of relative stability, known as euthymia, in between. Although prognosis for BD sufferers remains poor, treatment development has been restricted due to a paucity of validated animal models. Moreover, most models focus on the manic state of BD with li...

Late-onset bipolar disorder is rare and can be precipitated by organic brain disorders. While the association between hyperthyroidism and mania is well described, mania or hypomania precipitated by hypothyroidism is rare. The authors present late-onset bipolar disorder in a 72-year-old woman presenting with mania and psychosis, which appear to have been precipitated by autoimmune hypothyroidism...