We consider the planning and scheduling of production in a multitask/multistage batch manufacturing process typical of industries such as chemical manufacturing, food processing, and oil refining. We allow instances in which multiple sequences of tasks may be used to produce end products. We formulate the problem as a mixed-integer linear program and show that the linear programming relaxation ...

In this paper we present a new methodology for modelling manufacturing discrete systems. The main contribution is to cleary differenciate the system and the activity that it performs. Such difference allows to create relationships between them, wich are essential for the model formulation. Through the proposed methodology we aim to developed an easy to use simulation tool for modelling the most...

We consider the planning and scheduling of production in a multi-task/multi-stage batch manufacturing process typical of industries such as chemical manufacturing, food processing, and oil refining. We allow instances in which multiple sequences of tasks may be used to produce end products. We formulate the problem as a mixed integer linear program and show that the linear programming relaxatio...

2 Department of Mechanical Engineering University of British Columbia Vancouver, B.C., V6T 1Z4 Abstract Optimal line design seeks to identify the best configuration of resources and allocation of tasks to satisfy criteria such as maximum throughput or minimum cost. Coupling several levels of the problem together provides a more comprehensive solution but can be difficult because of problem form...

The ability to assess and select new suppliers quickly and efficiently is a critical requirement for improving the agility of manufacturing supply chains. The Digital Manufacturing Market (DMM) is a web-based platform for intelligent supply chain configuration. This research enhances the DMM’s performance by developing a column generation method for solving the supplier selection problem. The o...

The paper presents a dropwise additive manufacturing process for pharmaceutical products (DAMPP) as an alternative to conventional methods. This mini manufacturing process for the production of personalized pharmaceutical products utilizes drop-on-demand (DoD) printing technology for the deposition of active pharmaceutical ingredient (API) onto edible substrates. Here we present a process contr...

The present article gives an introduction and general overview on process validation of pharmaceutical manufacturing process especially tablet manufacturing process. The principal objective of dosage form design is to achieve a predictable therapeutic response to a drug included in a formulation which is capable of large scale manufacture with reproducible product quality. Solid dosage forms in...

Metalworking fluids (MWFs) are harmful to the environment and to the health of workers, resulting in pressures to re-design them in accordance with sustainable manufacturing principles. In this paper, we review research being performed at the University of Michigan to minimize the life cycle environmental and health impacts of metalworking fluids while simultaneously improving manufacturing per...

Consider the production of a single consumable product that is fabricated in a process of stages that is subject to an uncertain environment. There are a number of workstations on each stage that have different operating parameters. The workstations are subject to the discrete events of repair, failure, and preventive maintenance that generate a jump in the state of the system. Between each sta...

Downstream waste from industry and other industrial processes could increase concentration of heavy metals in water. These pollutants are commonly removed by adsorption because it is an effective and economical method. Previously, we reported adsorption capacity of a chitosan/polyurethane/titanium dioxide (TiO₂) composite for three ions in a dynamic wastewater system. There, increasing the chit...