A gas chromatography-mass spectrometry (GC-MS) and a liquid chromatography tandem mass spectrometry (LC-MS/MS) method were validated for quantifying endogenous and exogenous hair concentrations of gamma-hydroxybutyrate (GHB). The GC-MS method is based on overnight extraction of 25 mg hair in NaOH at 56 °C, liquid/liquid extraction in ethylacetate and trimethylsylil derivatization; analysis is b...

The essential oil extracted from the soft coral of Sinularia sp. have been extracted by soxhlet and analyzed by gas chromatography coupled to mass spectrometry (GC–MS). The principal compounds were found to be δ-Cadinene (12.4%), α-terpinene (10.7%) and α-Muurolene (8.3%). It is worth mentioning the presence of sesquiterpenes and diterpenes as main compounds of the essential oil. This is the fi...

A fast gas chromatography-mass spectrometry (GC-MS) method with minimum sample preparation is described for early diagnosis of tuberculosis (TB). The automated procedure is based on the injection of sputum samples which are then methylated inside the GC injector using thermally assisted hydrolysis and methylation (THM). The THM-GC-MS procedure was optimized for the injection of sputum samples. ...

In recent years, comprehensive two-dimensional gas chromatography (GC x GC) has attained increasing attention for its outstanding separation potential and capability to solve demanding analytical tasks. Trace level analysis of pesticides residues in complex food matrices represents such a demanding task. For some commodities, such as baby food, the requirements on method detection limits are ve...

Compared to other analytical platforms, comprehensive two-dimensional gas chromatography coupled with mass spectrometry (GC×GC-MS) has much increased separation power for analysis of complex samples and thus is increasingly used in metabolomics for biomarker discovery. However, accurate peak detection remains a bottleneck for wide applications of GC×GC-MS. Therefore, the normal-exponential-Bern...

Pesticide residue analysis in medicinal herbs is a challenging task because of the matrix effect and its influence on quantitative despite continuous development several new analytical methods instrumentations. In this study, modified QuEChERS method was developed for indoxacarb by using conventional instrument, gas chromatography micro-electron-capture-detector (GC–μECD), comparing it with chr...

The data presented in this article are related to the research article entitled "13C labeling analysis of sugars by high resolution-mass spectrometry for Metabolic Flux Analysis" (Acket et al., 2017) [1]. This article provides data concerning the comparison between the theoretically expected values of free sugars mass isotopomer composition with standards using our previous methods using low re...

During the investigation of aviation accidents, postmortem specimens from accident victims are submitted to the Federal Aviation Administration's Civil Aerospace Medical Institute (CAMI) for toxicological analysis. A case recently received by CAMI screened positive for the anticonvulsant medication carbamazepine (CBZ; Tegretol(®)) by gas chromatography-mass spectrometry (GC-MS). The CBZ found d...