A 70-year-old patient with chronic ischemic cardiomy-opathy (NYHA III, left ventricle ejection fraction (EFLV) = 15%, left bundle branch block (LBBB), percutaneous coronary intervention (PCI) left anterior descending artery (LAD) in 2006 and right coronary artery (RCA) in 2007), after an episode of sustained VT, terminated pharmacologically , was qualified for a cardiac resynchronization therap...

Mabuchi introduced the Mabuchi functional in [Mb1], and it turns out that it is very useful for dealing with Kähler metrics with constant scalar curvatures on compact manifolds (see [BM], etc.). One can also expect that the existence of Kähler metric with constant scalar curvature is almost equivalent to the existence of a lower bound of the Mabuchi functional (see, e.g., [Ti]). But for the cas...

For every n divisible by 4, we construct a square matrix H of size n, with coeecients 1, such that H H t nI mod 32. This solves the 32-modular version of the classical Hadamard conjecture. We also determine the set of lengths of 16-modular Golay sequences. 0. Introduction Hadamard matrices can be constructed from various binary sequences, either from Golay complementary sequences, or Williamson...

Preparation of biological macromolecules in the pure state requires that cells be disrupted, releasing and mixing the contents. Only the most stable and highly structured molecules can survive in the cellular “soup”, which contains proteases and nucleases that would be tightly controlled and sequestered in a normal living cell. Thus, as long as “activity” of polypeptides had to be measured by c...

Methylmercury is a toxic substance which accumulates in fish and other biota and causes toxicological problems when consumed by humans. Certain mercury resistant bacteria are able to convert the highly toxic methylmercury to a much less toxic form. Several mer operons, a group of genes which encode this function, have been cloned and characterized. However, they have been isolated and cloned fr...

To the Editor: There have been several reports of apparently high concentrations of creatine kinase (CK)-MB in the sera of cancer patients [1–4]. In several of these cases, the high activity resulted from the presence of macro CK types 1 and 2 [5]. False-positive results for CK-MB can occur if nonspecific assays such as immunoinhibition are used [6]. These atypical isoenzymes are not inhibited ...

Evidence is presented for the operation in nodules of at least four systems for restoring functional ferrous leghemoglobin (Lb2+) from its inactive, ferric form. (i) Reduction offerric leghemoglobin (Lb3+) by a reductase. The enzyme is a flavoprotein of 100 kDa with two equally sized subunits and exhibits a K. of 9 ,uM for soybean Lb3+ component a and a K. of 51 ,IM for NADH. NADPH is only 30% ...

Biochemical, structural and single amino acid level analysis of 49 Plasmodium falciparum protein regions (13 sporozoite and 36 merozoite proteins) has highlighted the functional role of each conserved high activity binding peptide (cHABP) in cell host-microbe interaction, involving biological functions such as gliding motility, traversal activity, binding invasion, reproduction, nutrient ion tr...