Mechanism-based inactivation (MBI) can mediate adverse reactions and hepatotoxicity from drugs, which is a result of their conversion into highly reactive metabolites catalyzed by enzymes such as cytochrome P450 3A (CYP3A). In the present research, we optimized key interaction domain fluorophore with target protein to develop two-photon fluorescent probe for CYP3A that involved in metabolism mo...

Objective: To describe the prevalence of burnout and its dimensions in undergraduate dental students, through a systematic review literature. Methods: A biomedical search was carried out PubMed database regarding measured with MBI-HSS MBI-SS questionnaires, English between 2002 2019. The studies were independently selected by two investigators according to eligibility criteria. Study bias analy...

An abstract is not available for this content so a preview has been provided. As you have access to content, full PDF via the ‘Save PDF’ action button.

An abstract is not available for this content so a preview has been provided. As you have access to content, full PDF via the ‘Save PDF’ action button.

An abstract is not available for this content so a preview has been provided. As you have access to content, full PDF via the ‘Save PDF’ action button.

We aimed to compare teams’ attack styles in Europe and South America elite football the two most valued domestic leagues both continents (Spanish La Liga & English Premier League Europe, Argentinian Superliga Brazilian Série A America). For this purpose, we used a sample of 84 teams 3,780 cases 1,214 games. Using an observational tool, analyzed performance indicators (goals, shots, dribbles...

Background Apathy, characterized by decreased interest, initiative, and emotional reactivity, is amongst the most common neuropsychiatric symptoms in dementia. However, apathy can emerge before dementia constitutes a domain of mild behavioral impairment (MBI), an at-risk state for incident cognitive decline MBI-apathy de novo emergence persistent dementia-free older adults may be driving factor...

An abstract is not available for this content so a preview has been provided. As you have access to content, full PDF via the ‘Save PDF’ action button.