The present research was conducted on 170 rats dividing into two groups. One group received HHKV extract at a dose of 2 g/kg/day continuously for 14 days. The other group received TCTN1 extract at a dose of 3 g/kg/day for 30 days. After 14 and 30 days of experiment, a half of each group received an electrical shock and the remainder didn't receive such treatment Malonyl dialdehyd (MDA) of rat’s...

ion of the design process to a higher level called system-level. At the system-level, there is no difference between hardware and software. Great productivity gains can be achieved by starting design from this level. In system-level design, there are several programming languages called system-level description languages, proposed to facilitate the design methodology such as SpecC [20], SystemC...

The Model Driven Architecture (MDA) describes software development based on models on different levels of abstraction. The development process is outlined as a sequence of model transformations which add specific details to the software models with each subsequent step. The OMG MDA guide refers to the computation independent model (CIM) as the highest level of abstraction. However this model ty...

Transmission assessment surveys (TAS) for lymphatic filariasis have been proposed as a platform to assess the impact of mass drug administration (MDA) on soil-transmitted helminths (STHs). This study used computer simulation and field data from preand post-MDA settings across Kenya to evaluate the performance and costeffectiveness of the TAS design for STH assessment compared with alternative s...

OBJECTIVE The aim of the present study was to investigate influence of oxidative stress on newborn organism, in terms of the dynamics of malondialdehyde (MDA) concentration changes and of the activities of selected antioxidants in asphyxial newborns on the 1st and 5th day of life. METHOD In the group of 62 preterm and term asphyxial newborns, characterized by the presence of asphyxial criteri...

The p53 tumor suppressor protein is a principal mediator of growth arrest, senescence, and apoptosis in response to a broad array of cellular damage. p53 is a substrate for the ubiquitin-proteasome system, however, the ubiquitin-conjugating enzymes (E2s) involved in p53 ubiquitination have not been well studied. UBE2Q1 is a novel E2 ubiquitin conjugating enzyme gene. Here, we investigated the e...

OBJECTIVES The aim of this study was to evaluate 8-hydroxydeoxyguanosine (8-OHdG) and Malondialdehyde (MDA) levels, and superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities in whole saliva of patients with chronic periodontitis. Moreover, the relationship among the oxidative damage biomarkers, antioxidant enzymes activities and clinical periodontal status were investigated. ...

Obstructive sleep apnea is characterized by upper airway collapse, leading to intermittent hypoxia (IH). It has been postulated that IH-induced oxidative stress may contribute to several chronic diseases associated with obstructive sleep apnea. We hypothesize that IH induces systemic oxidative stress by upregulating NADPH oxidase, a superoxide-generating enzyme. NADPH oxidase is regulated by a ...

Aim of the present study is to investigate the total antioxidant capacity (TAC) and lipid peroxidation end product, malondialdehyde (MDA) concentration in seminal plasma of fertile and infertile men and its relationship with different spermatozoa parameters. Semen samples were collected from 15 fertile men (normozoospermic as control) and 40 infertile men (15 oligozoospermic, 17 asthenozoosperm...

OBJECTIVE Methotrexate (MTX) is known to have deleterious side effects on lung tissue. We aimed to investigate the effects of erythropoietin (EPO) and N-acetyl-cysteine (NAC) on MTX-induced lung injury in rats. STUDY DESIGN Animal experiment. MATERIAL AND METHODS Twenty-six female Sprague-Dawley rats were divided into 4 groups. Sham group, 0.3 mL saline; MTX group, 5 mg/kg MTX; EPO group, 5...