نتایج جستجو برای: mdm2 snp309
تعداد نتایج: 4579 فیلتر نتایج به سال:
There has been considerable progress in analyzing p53 pathway integrity in CLL. Routine fluorescent in situ hybridization (FISH) analysis detects deletion of the region of chromosome 17 (17p13 ), which includes the gene (TP53) coding for p53. 17p13 is a powerful predictor of resistance to therapy with purine analogues and alkylating agents and poor prognosis in CLL. Approximately 80% of CLL pat...
Introduction: Immunological processes play an important role in recurrent spontaneous abortion(RSA). According to studies, T lymphocytes and natural killer cells(NK cells) are two effective cell groups in RSA. The aim of this study was to study the percentage and absolute number of natural killer(NK) cells in women with RSA of unknown etiology. Methods: A total of 24 women with history of recu...
PURPOSE The Arg/Pro polymorphism in codon 72 of p53 was recently associated with age of onset of colorectal cancer in Lynch syndrome. A novel polymorphism in the promoter region of MDM2 was associated with age of cancer onset in Li-Fraumeni syndrome. We studied the influence of both polymorphisms on age of onset in Lynch syndrome and of the p53 polymorphism also in sporadic colorectal cancer. ...
MDM2 SNP309 polymorphism is associated with lung cancer risk in women: A meta-analysis using METAGEN
Background & Aims: Leukemia is a type of malignancy of the hematopoietic tissue that accompanies the incomplete development and proliferation of white blood cells. In acute lymphoid leukemia (ALL), many lymphocytes that have not yet completely evolved, are impaired and increasingly found in peripheral blood and bone marrow. MDM2 is a proto-oncogene with E3 ubiquitin ligase activity that acts as...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید