Hypertension increases mechanical force on the arterial wall by as much as 30%, resulting in marked alterations in signal transductions and gene expression in vascular smooth muscle cells (VSMCs) that contribute to matrix protein synthesis, cell proliferation, and differentiation. How the mechanical stimuli are converted into a biological signal in cells has yet to be studied. We investigated t...

Cement-based materials prepared with activated water induced by a magnetic field or electric represent possible solution to environmental issues caused the worldwide utilization of chemical admixtures. In this contribution, electric- and magnetic-activated have been produced. The workability mechanical properties cement mortar investigated. results indicate that pH absorbance (Abs) values varie...

Mechanosensitive channels serve as essential sensors for cells to interact with their environment. The identity of mechanosensitive channels that underlie somatosensory touch transduction is still a mystery. One promising mechanotransduction candidate is the Transient Receptor Potential Ankyrin 1 (TRPA1) ion channel. To determine the role of TRPA1 in the generation of mechanically-sensitive cur...

AIMS Monocytes play a significant role in the development of atherosclerosis. During the process of inflammation, circulating monocytes become activated in the blood stream. The consequent interactions of the activated monocytes with the blood flow and endothelial cells result in reorganization of cytoskeletal proteins, in particular of the microfilament structure, and concomitant changes in ce...

the silver spr chip was modified by alkaline-silane condensation with aminopropyltriethoxysilane (aptes) in naoh aqueous solution at different times. silver sputtered slides coated with aptes were immersed in naoh solution, enabling us to produce silver surfaces homogeneously covered with aptes. the surface properties of grafted aptes on sputtered silver surface as a occasion of time were studi...

BACKGROUND Orofacial inflammatory pain is likely to accompany referred pain in uninflamed orofacial structures. The ectopic pain precludes precise diagnosis and makes treatment problematic, because the underlying mechanism is not well understood. Using the established ectopic orofacial pain model induced by complete Freund's adjuvant (CFA) injection into trapezius muscle, we analyzed the possib...

Tibia fracture followed by limb immobilization in rats evokes nociceptive and vascular changes resembling complex regional pain syndrome type I (CRPS I). Previously we observed that substance P (SP) and interleukin-1beta (IL-1beta) signaling contribute to chronic regional nociceptive sensitization in this model. It is known that inflammasome multi-protein complexes containing caspase-1 and NALP...

In this study, a top cover system is investigated as a control for emissions during the aftercare of new landfills and for old landfills where biogas energy production might not be profitable. Different materials were studied as landfill cover system in lab-scale columns: mechanical-biological pretreated municipal solid waste (MBP); mechanical-biological pretreated biowaste (PB); fine (PBSf) an...

1. The mesothoracic wings of tettigoniid insects are used in song production and flight; the metathoracic wings in flight only. In Neoconocephalus triops the wing stroke frequency during flight is about 25 Hz; the frequency during singing about 100 Hz. 2. The twitch duration of mesothoracic, first tergocoxal (Tcxl) wing muscles is only about one-half the duration of the upstroke or downstroke p...