To determine the efficacy of single and multiple administrations Poloxamer 188 (P188) in saving meniscal cells following an injurious impact. Meniscal explants were harvested from both lateral medial menisci Flemish Giant rabbits. After a 24-h incubation period, subjected to 50% impact strain simulate traumatic joint injury, then placed media with or without supplemented P188. Temporal P188 ove...

BACKGROUND Increased contact stress with a femoral resurfacing prosthesis implanted in the medial femoral condyle and a non-functional meniscus is of concern for potential deleterious effects on tibiofemoral contact mechanics. METHODS Peak contact pressures were determined in seven fresh frozen human cadaveric specimens using a pressure sensitive sensor placed in the medial compartment above ...

The mechanical functions of the menisci may be partially performed through the fluid pressurization in articular cartilages and menisci. This creep behavior has not been investigated in whole knee joint modeling. A three-dimensional finite element knee model was employed in the present study to explore the fluid-flow dependent creep behaviors of normal and meniscectomy knees. The model included...

PURPOSE To measure the upper and lower tear menisci in patients with aqueous tear deficiency (ATD) dry eye by real-time optical coherence tomography (OCT) and to determine the most effective meniscus variables for the diagnosis of dry eye. METHODS Eyes of 48 pre-screened ATD patients were compared with those of 47 healthy subjects. Upper and lower tear menisci were imaged simultaneously by re...

Objective. Studies have shown that meniscal repairs have better outcomes over both partial and total meniscectomies. Tissue engineering strategies to repair meniscus tears have been explored using cell sources that involve a donor as well as a period of in vitro cell expansion before use. This study explored cell sources that could be easily harvested and rapidly isolated by enzymatic digestion...

BACKGROUND This study was designed to investigate the prevalence of the menisci lesions in national park workers and work factors affecting this prevalence. METHODS The study subjects were 698 workers who worked in 20 Korean national parks in 2014. An orthopedist visited each national park and performed physical examinations. Knee MRI was performed if the McMurray test or Apley test was posit...

BACKGROUND Meniscal repair is commonly performed concurrently with anterior cruciate ligament reconstruction (ACLR) in the acutely injured knee. No large-scale, prospective multicenter studies have evaluated the long-term success and patient-oriented outcomes after combined ACLR and meniscal repair. PURPOSE To define the operative success and patient-oriented outcome scores 6 years after comb...

PURPOSE To determine the influence of osteochondral defect size on defect rim stress concentration, peak rim stress, and load redistribution to adjacent cartilage over the weightbearing area of the medial and lateral femoral condyles in the human knee. METHODS Eight fresh-frozen cadaveric knees were mounted at 30 degrees of flexion in a materials testing machine. Digital electronic pressure s...