Introduction Testicular germ cell tumors with somatic-type malignancy, wherein teratomas transform into sarcomas, is drug resistant and has a poor prognosis. Case presentation A 43-year-old man presented left testicular tumor, multiple pulmonary metastases, mediastinal para-aortic lymph node metastases. The were diagnosed as tumors. After bleomycin, etoposide, cisplatin chemotherapy; right uppe...

DESCRIPTION A 24-year-old man presented with dyspnoea on exertion. Chest x-ray showed an enlargement of the upper anterior mediastinum (figure 1A). Chest CT showed a huge mass with the size of 7.6×4.8 cm in the upper anterior mediastinum (figure 1B). This mass compressed the main pulmonary artery trunk (MPA) and the left pulmonary artery. Transthoracic two-dimensional echocardiography also reve...

Three cases of primary mediastinal trophoblastic teratoma are described. One patient died from respiratory failure during the initial chemotherapy, Another patient with advanced disease is now apparently free from disease after multiple-drug chemotherapy. The third patient is alive and well four years after a combination of surgery, radiotherapy, and multiple-drug chemotherapy. In the diagnosis...

Mixed germ cell tumors with non-germ cell malignant components rarely occur in the anterior mediastinum. We report a case of a 34-year-old man who presented with an anterior mediastinum mass. Mixed germ cell tumor was initially diagnosed based on the pathologic findings of germinoma on thoracoscopic biopsy and clinical findings of elevated serum alpha-fetoprotein and beta-human chorionic gonado...

Germ cell tumor with somatic malignant transformation is an uncommon phenomenon occurring about 7% of all mediastinal teratomas. Among all transformed component, sarcoma appears to be the most frequent histology, followed by primitive neuroectodermal tumor (PNET) and adenocarcinoma. To our knowledge, there were 3 cases of colonic-type adenocarcinoma arising in a primary teratoma have been repor...