We used instrumental neutron activation analysis (INAA) to determine antimony in small quantities of hair from individuals living in an area of endemic leishmaniasis. The groups studied were 12 patients undergoing treatment with N-methylglucamine antimoniate, 34 patients who had received such treatment a year ago, and 17 control subjects (untreated) who were living in the same area. Patients re...

Background & Aims: It is more than half of a century that the drug of choice for treatment of cutaneous leishmaniosis (CL) has been pentavalent antimony compounds such as meglumine antimoniate (Glucantime). The aim of the present study was to evaluate the efficacy, relapse and treatment failure of intralesional Glucantime plus cryotherapy in the treatment of anthroponotic CL (ACL). Methods: The...

Canine gastrointestinal infection by Leishmania presenting large bowel involvement has been reported to date. This case series describes two dogs suffering from severe chronic small bowel diarrhea. Duodenal biopsies demonstrated granulomatous infiltration with intracytoplasmatic corpuscles of Leishmania amastigotes. Furthermore one of the dogs was diagnosed with protein-losing enteropathy (PLE)...