Background: Alzheimer Disease (AD) is an age-related neurodegenerative disorder with a progressive impairment of cognitive function. The pineal gland hormone melatonin (MEL) has been known as a protection agent against AD. However, the effect of melatonin in various doses is inconsistent. Objectives: In this study, we aimed to investigate two doses of MEL on learning and memory in the amyl...

The nonlinear response of nanoporous silicon optical waveguides is investigated using a novel pump-probe method. In this approach we use a two-frequency heterodyne technique to measure the pump-induced transient change in phase and intensity in a single measurement. We measure a 100 picosecond material response time and report behavior matching a physical model dominated by free-carrier effects...

Dendritic cells (DCs) phagocytose apoptotic influenza-infected monocytes and cross-present influenza antigen to CD8 T cells, generating a specific CTL response. We investigated whether apoptotic melanoma cells, presented by this mechanism, can lead to CTL responses to tumorassociated antigens and melanoma cells. Apoptotic HLA-A2 MEL-397 melanoma cells were internalized by HLA-A2 immature monocy...

Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Nanostructured materials exhibit low thermal conductivity because of the additional scattering due to phonon-bounda...

Nanostructured materials exhibit low thermal conductivity because of the additional scattering due to phononboundary interactions. As these interactions are highly sensitive to the mean free path (MFP) of phonons, MFP distributions in nanostructures can be dramatically distorted relative to bulk. Here we calculate the MFP distribution in periodic nanoporous Si for different temperatures, using ...

Metallic foams with pore sizes from 250 lm to 2 mm have been a subject of research for over two decades due to their high surface area, which allows for a variety of applications, such as thermal and sound insulation. Recently, processing of metallic foams at the nanoscale (pores sizes less than 100 nm) has opened the door to new and interesting applications, such as sensors and actuators. In g...