Purpose: To determine the effectiveness of external application Jidesheng snake tablets, trehalose glycerin mud, and hydroquinone cream in treatment melasma.
 Methods: The study was conducted on 60 patients with melasma who were treated Affiliated Yueqing Hospital Wenzhou Medical University between January 1, 2021, 31, 2022. randomly but equally assigned to two groups (study control). grou...

Objective: To evaluate the efficacy and safety patient experience of Intense pulse light (IPL) in our population. Study Design: Quasi-experimental. Setting: Department Dermatology, HIT Hospital. Period: December 2022 to May 2023. Material & Methods: 34 females with melasma fulfilling inclusion criteria were selected for this study. Exclusion include thyroid disease, pregnant lactating mothe...

BACKGROUND Although asymptomatic, melasma inflicts significant impact on quality of life. MELASQoL is the main instrument used to assess quality of life associated with melasma, it has been validated in several languages, but its latent dimensional structure and psychometric properties haven´t been fully explored. OBJECTIVES To evaluate psychometric characteristics, information and dimensiona...

Melasma is a chronic acquired hypermelanosis of the skin, characterized by irregular brown macules symmetrically distributed on sun-exposed areas of the body, particularly on the face. It is a common cause of demand for dermatological care that affects mainly women (especially during the menacme), and more pigmented phenotypes (Fitzpatrick skin types III-V). Due to its frequent facial involveme...

Exogenous ochronosis is an infrequent dermatosis characterized as a dark blue hyperpigmentation localized where the causing agent was applied. It may be caused by the use of systemic medication such as antimalarials and by the use of topic substances such as phenol, resorcinol, benzene, or hydroquinone, which is a fenolic compound with depigmentation action, largely used in the treatment of mel...

Background: Melasma is an acquired therapeutically problematicdisease characterized by symmetrical facial hypermelanosis. Theaim of this study was to evaluate the efficacy of azelaic acid20% cream in the treatment of melasma in Iranian patients andcompare it with hydroquinone 4% cream which has been thestandard treatment.Method: The study was an open clinical trial with a split-facedesign. All ...

BACKGROUND Melasma treatment remains challenging despite various laser systems available, because of potential side-effects and high recurrence rates. OBJECTIVE Non-ablative fractionated photothermolysis (FP) is a promising therapeutic method, long-time results comparing treated vs. non-treated site are lacking. METHODS A total of 14 patients were treated with FP in a split-face mode with s...

The picosecond lasers have shown to effectively treat tattoo pigments that are intractable to previous multiple Q-switched (QS) laser treatments. Therefore we hypothesized that a picosecond laser would show better efficacy with minimal adverse events in the treatment of melasma and post-inflammatory hyperpigmentation (PIH) that are difficult to treat with conventional QS lasers. Two patients wi...

BACKGROUND A 1,927-nm wavelength was recently added to the 1,550-nm erbium-doped fiber laser. This wavelength possesses a higher absorption coefficient for water than the 1,550-nm, conferring greater ability to target epidermal processes such as dyschromia. OBJECTIVE To evaluate the efficacy and safety of a novel 1,927-nm fractional thulium fiber laser in the treatment of melasma. METHODS F...

BACKGROUND Melasma is a common pigmentary disorder that remains resistant to available therapies. Facial resurfacing with the pulsed CO2 laser has been reported successful but requires significant downtime, and there is a risk of adverse sequelae. OBJECTIVE To determine if melasma will respond to a new treatment paradigm, fractional resurfacing. METHODS Ten female patients (Fitzpatrick skin...