BACKGROUND Literature regarding acute human toxicity of mycophenolate mofetil (MMF) and enteric-coated mycophenolate sodium (EC-MPS) is limited. OBJECTIVES Our objectives were to describe all cases of overdose with MMF or EC-MPS reported to the Swiss Toxicological Information Centre (STIC) or in the literature between 1995 and 2013. Therefore, we performed an observational case-series and sys...

Cardiac dysfunction is a common cause of death among pediatric patients with mutations in the lysosomal hydrolase α-l-iduronidase (IDUA) gene, which causes mucopolysaccharidosis type I (MPS-I). The purpose of this study was to analyze adrenergic regulation of cardiac hemodynamic function in MPS-I. An analysis of murine heart function was performed using conductance micromanometry to assess in v...

Medial patellar subluxation (MPS) is an often unrecognized cause of instability and easily mistaken for lateral subluxation. MPS occurs as the patella rotates up on side a longitudinal axis due to laxity retinaculum in extension. This can occur naturally or after release. In addition, medial femoral trochlea undeveloped shallow early flexion, thus not providing bony support resist combination f...

Cereals–soybean intercropping is not well studied, despite the importance of these crops in increasing agricultural profitability and ensuring nutritional food security Southeast Asia. We compared different practices (IPs) with monocropping (MPs) for their yield economic performance by small-scale farms without mechanization. The treatments were IPs rice–maize, rice–soybean, or maize–soybean MP...

BACKGROUND Current studies comparing musculoskeletal pain levels between the genders focus on a single point in time rather than measuring change over time. The purpose of this study is to compare pain levels between males and females before and after treatment. METHODS Eleven different patient cohorts (3,900 patients) included in two prospective outcome databases collected pain data at basel...

this article reviews will focus on the concept and formation of micro particles (mps) in circulation and their role in transfusion medicine and immune system. mps are cell membrane derived vesicles which express markers of their parent cells and are found in circulation at low levels. exact functions of mps are unclear. in here, physiological almost all types of circulating mps including platel...

BACKGROUND : Therapy with mycophenolate mofetil (MMF) has become a valuable therapeutic option in children with autoimmune disease. MMF prescription in children with autoimmune diseases differs from that in transplant recipients in terms of different dosing regimen, and concomitant administration of other immunosuppressive medications. Recently, another formulation of the same active compound, ...

introduction: human resources are one of the factors most effective on the success or failure of an organization and service motivation is a factor which affects the quality and quantity of activity of an organization. the present study aimed to determine the motivating potential score (mps) of medical record staff of training hospitals in isfahan, iran, over the years of 2011-2012. methods: th...

The hips are frequently involved in inheritable diseases which affect the bones. clinical and radiological presentation of these may be very similar to common hip disorders as developmental dysplasia hip, osteoarthritis avascular necrosis, so diagnosis easily overlooked treatment suboptimal. Mucopolysaccharidosis (MPS) Mucolipidosis (ML II III) lysosomal storage with multisystemic involvement. ...