A 63-year-old woman with abdominal pain and melena developed a palpable, purpuric rash and acute kidney injury. Skin and kidney biopsy confirmed Henoch-Schönlein purpura. Upper endoscopy revealed diffuse, circumferential, black-appearing mucosa of the esophagus consistent with acute esophageal necrosis (AEN), also known as black esophagus. AEN is a very rare cause of gastrointestinal hemorrhage...

Intra luminal gallbladder bleeding is a rare cause of hemobilia that results in upper gastro-intestinal bleeding. In this case report we present a patient who presented with melena and eventually was diagnosed as bleeding from an ulcer in the gallbladder which was induced by gallstones and eroded into the cystic artery. Surgery revealed perforation of gallbladder which was the result of a press...

Holbrook C, Saleem N. BMJ Case Rep 2017. doi:10.1136/bcr-2017-220221 Description A 54-year-old Caucasian woman with no significant medical history presented to her primary care physician with chief complaints of right-sided abdominal dull pain and distension. There were no constitutional symptoms or other complaints such as nausea, vomiting, constipation, diarrhoea, melena or hematochezia. She ...

Symptomatic gastric malignancy usually presents with symptoms which mimic peptic ulcer disease.Usual presenting features include weight loss and abdominal pain. Other symptoms include nausea, vomiting, dysphagia, melena and early satiety. Gastric malignancy presenting with hemetemesis, macular skin lesions of DIC and low backache due to bone metastasis from the primary is rare. Also bone metast...

A man taking antithrombotic agents was admitted because of melena. Upper gastrointestinal endoscopy revealed a large, pedunculated polyp bleeding from erosions on its top. The polyp was endoscopically resected, and histopathologically diagnosed as Brunner's gland hyperplasia. It is commonly encountered as a small, raised lesion, but may enlarge or bleed. We report this case, with a review of th...

Patients: 921 patients > 18 years of age (mean age 65 y, 68% men) who were hospitalized with severe, acute upper GI bleeding (hematemesis, bloody nasogastric aspirate, or melena). Exclusion criteria included massive exsanguinating or lower GI bleeding; recent trauma or surgery; Rockall score = 0 (low rebleeding risk) with hemoglobin (Hgb) level > 12 g/dL; or an acute coronary syndrome, symptoma...

The diagnosis of an intraperitoneal abscess is usually difficult. The clinical manifestation may vary, fever and abdominal discomfort ranging from minimal to severe. Anorexia, nausea, vomiting, and diarrhea or constipation are common features. A 54-year old male, after two weeks hospitalization referred with the diagnosis of appendix infiltrate and melena. He was treated with TPN, omeprazole, s...