This study aimed to determine whether patients with statin-induced myopathy could be identified using the United Kingdom Clinical Practice Research Datalink, whether DNA could be obtained, and whether previously reported associations of statin myopathy with the SLCO1B1 c.521T>C and COQ2 rs4693075 polymorphisms could be replicated. Seventy-seven statin-induced myopathy patients (serum creatine p...

facioscapulohumeral muscular dystrophy (fshd) is a common inherited muscular dystrophy presented clinically with slowly progressive weakness and wasting of facial and limb muscles and rare bulbar muscle involvement. we present herein a 70-year-old man who was a known case of fshd with complaint of 15-day history of progressive difficulty in chewing and dysarthria and was found to have myastheni...

conclusions increasing dependency in adl is accompanied by increasing dependency in iadl. in the past, the duty of health care providers was saving the life of veterans due to injuries while at present, because these injuries occurred in young and healthy individuals, the need for increased function is being highlighted. background the iran-iraq imposed war lasted eight years and was one of the...

human t-cell lymphotropic virus (htlv) types 1 and 2 belong to the oncorna group of retroviridae, a large family of viruses, grouped initially by pathogenic features, but later revised on the basis of genome structure and nucleotide sequence. htlv-i was the first discovered human retrovirus to be associated with a malignancy in 1980. the malignancy, first described by uchiyama and co-workers in...

case presentation a 28-year old chinese female was treated with carbimazole (cmz) for graves’ disease with hyperthyroidism. two weeks later, she developed myalgia and proximal muscle weakness. investigations showed evidence of myopathy. cmz was stopped and rapid improvement of clinical condition and biochemical parameters ensued. conclusions rapid decrement of thyroid hormone level is recognize...

BACKGROUND Published studies regarding statin-associated myopathy may describe more dramatic patient presentations, potentially leading to inaccurate characterization of the condition. Furthermore, long-term outcomes and responses to statin rechallenge in patients with statin-associated myopathy are largely unknown. METHODS The University of Wisconsin Hospital and Clinics Medical Informatics ...

A renal transplant patient who presented with a painful, proximal myopathy due to systemic calciphylaxis is described. The myopathy preceded the characteristic skin and soft tissue necrosis. Systemic calciphylaxis should be considered in a dialysis or a renal transplant patient presenting with a painful proximal myopathy even in the absence of necrotic skin lesions.

Two patients with muscle weakness caused by amyloid myopathy are described. Characteristic features such as pseudohypertrophy and abnormal firmness, and tumours of muscles were absent. It is suggested that muscle weakness in amyloid myopathy is caused by layers of amyloid covering muscle fibres. In middle aged or elderly patients with proximal muscle weakness the diagnosis of amyloid myopathy s...

Key points • Fingerprint body is a rare congenital myopathy. • Only 5 cases of fingerprint myopathy have been described to date. • Fingerprint myopathy is defined by subsarcolemmal inclusions on muscle biopsy; the inclusions have a characteristic lamellar pattern on electron microscopy. • The genetic basis of fingerprint myopathy is not yet known. • An increasing number of protein aggregate myo...

    Human T-cell lymphotropic virus (HTLV) types 1 and 2 belong to the Oncorna group of retroviridae, a large family of viruses, grouped initially by pathogenic features, but later revised on the basis of genome structure and nucleotide sequence. HTLV-I was the first discovered human retrovirus to be associated with a malignancy in 1980. The malignancy, first described by Uchiyama and co-worker...