The ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs) are a group of proteases that are found both in mammals and invertebrates. Since the prototype ADAMTS-1 was first described in 1997, there has been a rapidly expanding body of literature describing this gene family and the proteins they encode. The complete human family has 19 ADAMTS genes, together with three members ...

Matrix metalloproteinases (MMPs) are a gene family of neutral proteases that are important in normal development, wound healing, and a wide variety of pathological processes, including the spread of metastatic cancer cells, arthritic destruction of joints, atherosclerosis, and neuroinflammation. In the central nervous system (CNS), MMPs have been shown to degrade components of the basal lamina,...

Objective: Collagen is one of the main components in connective tissue (CT) and contributes to background toughness beef. It known that living animals, collagen can be degraded remodeled by collagenase matrix metalloproteinases (MMP); however, it unclear if MMP impact CT texture during postmortem aging Therefore, this study aimed understand how activity may degradation beef three different cuts...

Matrix metalloproteinases (MMPs) occupy a central role in embryogenesis and in normal physiological conditions, such as proliferation, cell motility, remodeling, wound healing, angiogenesis, and key reproductive events. MMPs form a multigenic family of proteolytic, zinc-dependent enzymes, with 26 members described until present, displaying multidomain structures and substrate specificities. MMP...