Malaria is a parasitic disease with limited chemotherapy options. Chemotherapy options are limited; moreover, drug resistant frequently occurs. The speed of drug development should be faster to overcome the emerging drug resistance. In the current study, a series of quinolone derivatives were subjected to quantitative structure activity relationship to identify the ideal physicochemical charact...

in this paper the general relatively isotropic l -curvature finsler metrics are studied. it isshown that on constant relatively landsberg spaces, the concepts of weakly landsbergian, landsbergianand generalized landsbergian metrics are equivalent. some necessary conditions for a relativelyisotropic l -curvature finsler metric to be a riemannian metric are also found.

Is is known that the loop space associated to a Riemannian manifold admits a quasi-symplectic structure. This article shows that this structure is not likely to recover the underlying Riemannian metric by proving a result that is a strong indication of the “almost” independence of the quasi-symplectic structure with respect to the metric. Finally conditions to have contact structures on these s...