for the Symposium on Innovative Polymers for Controlled Delivery 1 TAILOR-MADE COPOLYMERS FOR RESPONSIVE DRUG DELIVERY NANOSYSTEMS Sébastien Cajot, Christine Jérôme Center for Education and Research on Macromolecules (CERM), University of Liege, B6 Sart tilman, B-4000 Liege, Belgium. e-mail: [email protected] Summary Amphiphilic macromolecules combining a biodegradable and a bioeliminable block...

Lattice Monte Carlo and off-lattice molecular dynamics simulations of h1t4 and h4t1 ~head/tail! amphiphile solutions have been performed as a function of surfactant concentration and temperature. The lattice and off-lattice systems exhibit quite different self-assembly behavior at equivalent thermodynamic conditions. We found that in the weakly aggregating regime ~no preferred-size micelles!, a...

Polymers based on renewable resources are promising candidates for replacing common organic polymers, and thus, for reducing oil consumption. In this contribution we report the microwave-assisted synthesis of block and statistical copolymers from 2-ethyl-2-oxazoline and 2-"soy alkyl"-2-oxazoline via a cationic ring-opening polymerization mechanism. The synthesized copolymers were characterized ...

The thermodynamics of conventional surfactants, block copolymers and their mixtures in water was described to the light of the enthalpy function. The two methodologies, i.e. the van't Hoff approach and the isothermal calorimetry, used to determine the enthalpy of micellization of pure surfactants and block copolymers were described. The van't Hoff method was critically discussed. The aqueous co...

Sulfobetaines (SBs) are a class of zwitterionic surfactants with a reputation for enhancing colloidal stability at high salt concentrations. Here, we present a systematic study on the self-assembly of SB amphiphiles (sultaines or hydroxysultaines) in aqueous solutions, as a function of chain length and composition, ionic strength, and in the presence of alkanethiol-coated Au nanoparticles (GNPs...