Background: Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most significant human pathogens that cause both nosocomial and community-acquired infections worldwide which are associated with high morbidity and mortality rates with rapid development of resistance. Honey is one of the oldest traditional medicines considered to be important in the treatment of several human ailment...

Abstract Staphylococcus aureus is one of the most common pathogens in biofilm-associated chronic infections. S. living within biofilms evades host immune response and more resistant to antibiotics than planktonic bacteria. In this study, we generated with low high levels biofilm formation using rbf (regulator formation) gene performed a BioTimer assay determine minimum inhibitory concentration ...

AIM The aim of this study was to evaluate the minimum bactericidal concentrations (MBC) of root-end filling materials ProRoot MTA, MTA Angelus and IRM. MATERIALS AND METHODS Macrodilution broth method was used. Microorganisms used were: Staphylococcus aureus (ATCC 29213), Enterococcus faecalis (ATCC 29212) and Streptococcus mutans. Serial two-fold dilutions of root-end filling samples were pr...

This study investigated the physiology and behaviour following treatment with ortho-phthalaldehyde (OPA), of Pseudomonas fluorescens in both the planktonic and sessile states. Steady-state biofilms and planktonic cells were collected from a bioreactor and their extracellular polymeric substances (EPS) were extracted using a method that did not destroy the cells. Cell structure and physiology af...

A series of metal-containing epoxy polymers have been synthesized by the condensation of epichlorohydrin (1-chloro-2,3-epoxy propane) with Schiff base metal complexes in alkaline medium. Schiff base was initially prepared by the reaction of 2,6 dihydroxy 1-napthaldehyde and o-phenylenediamine in 1 : 2 molar ratio and then with metal acetate. All the synthesized compounds were characterized by e...

This research aimed to investigate the phytoconstituents and antibacterial effects of methanol ethyl acetate stem bark extracts Detarium microcarpum (DM). The phytochemicals were detected quantified while activity against Escherichia coli, Staphylococcus aureus, Salmonella typhi was established determining zone inhibition (ZI), minimum inhibitory concentration (MIC), bactericidal (MBC). Phytoch...

Linear, dimeric, tetrameric, and cyclic peptides derived from lactoferricin B-containing non-natural amino acids and the RWQWR motif were synthesized, purified, and characterized using RP-HPLC, MALDI-TOF mass spectrometry, and circular dichroism. The antibacterial activity of peptides against Escherichia coli ATCC 11775, Stenotrophomonas maltophilia ATCC 13636, and Salmonella enteritidis ATCC 1...

Radix aucklandiae from Yunnan Province in China is a significant medicinal plant. In the present study, the essential oil composition from Radix aucklandiae roots was investigated by gas chromatography-mass spectrometry (GC-MS). A total of 23 compounds representing 57.95% of the essential oil were tentatively identified. The main constituents were eremanthin (12.74%), d-Guaiene (6.26%), ζ-Himac...

Three new diphenyl ether derivatives-phomaethers A-C (1-3) and five known compounds-including a diphenyl ether analog, 2,3'-dihydroxy-4-methoxy-5',6-dimethyl diphenyl ether (4); and four isocoumarin derivatives, diaportinol (5), desmethyldiaportinol (6), citreoisocoumarinol (7), and citreoisocoumarin (8)-were isolated from a gorgonian-derived fungus Phoma sp. (TA07-1). Their structures were elu...