Sergentomyia sintoni is the natural vector of Sauroleishmania species of lizards. This sandfly isabundance in and around the burrows of great gerbils. S. sintoni was collected from peridomestic animalshelters, inside and around houses and also from the nearby burrows of the gerbil reservoir hosts,Rhombomys opimus, in several provinces of Iran. Mitochondrial Cytochrome b (Cyt b) of sandflies, wh...

A new genetic variation and potential haplotype of Bactericera cockerelli was identified based on the analysis mitochondrial region Cytochrome Oxidase subunit I two populations from greenhouses in Villa Unión, Durango Saltillo, Coahuila, Mexico. found base 247 a 500 bp amplified mtCOI gene, this change implies substitution an adenine (A) to Guanine (G), mutation detected insects collect their p...

Myxothiazol, an antibiotic from Myxococcus fulvus, which inhibits mitochondrial respiration in the bc1 complex of the respiratory chain, has effects on the redox components of isolated succinate-cytochrome c reductase complex which suggest that it interacts with both cytochrome b and the iron-sulfur protein of the bc1 complex. The inhibitor appears to increase the midpoint potentials of cytochr...

Granzyme B (GraB) is required for the efficient activation of apoptosis by cytotoxic T lymphocytes and natural killer cells. We find that GraB and perforin induce severe mitochondrial perturbation as evidenced by the release of cytochrome c into the cytosol and suppression of transmembrane potential (Deltapsi). The earliest mitochondrial event was the release of cytochrome c, which occurred at ...

Damage to the small intestine secondary to heat stroke is a major factor in heat stroke-related morbidity and mortality. However, the underlying mechanisms by which heat stroke causes small intestinal lesions and dysfunction remain unclear. To explore the pathogenesis of small intestinal tissue and epithelial cell injury, the SW480 cell heat stress model and the mice heat stroke model were esta...

Objective: Extracts of Anchomanes difformis (AD) are used in folkloric medicine to treat several diseases and infections. However, their roles in mitochondrial permeability transition pore opening are not known. Material and Methods: The viability of mitochondria isolated from Wistar rat liver used in this experiment, was assessed by monitoring their swel...

It is well recognized that mitochondrial dysfunction contributes to neurodegeneration occurring in Alzheimer's disease (AD). However, evidences of mitochondrial defects in AD peripheral cells are still inconclusive. Here, some mitochondrial-encoded and nuclear-encoded proteins, involved in maintaining the correct mitochondria machine, were investigated in terms of protein expression and enzymat...

Analysis of a riverine species flock 1 ABSTRACT We have discovered surprising undescribed diversity within a clade of mormyrid electric fish in our recent collections from the Ogooué and Ntem River basins of Gabon, Africa. We recognize 38 distinct forms within this group on the basis of unique morphologies and electric organ discharge (EOD) characteristics of which only four clearly correspond ...

We studied the molecular composition of muscle mitochondria to evaluate whether the contents of cytochromes or adenine nucleotide translocase (ANT) or phospholipid acyl compositions reflect differences in mitochondrial oxidative capacities. We isolated mitochondria from three vertebrates of similar size and preferred temperature, the rat (Rattus norvegicus), the cane toad (Bufo marinus) and the...

persian gazelle, gazella subgutturosa, exists throughout arid and semiarid regions of iran and has a key role in these frail ecosystems. habitat degradation and population decline has placed it on the list of vulnerable species in 2008. the phylogenetic relationships of three persian gazelle populations in the central part of iran (i.e. ghamishlou national park and wildlife refuge, mouteh wildl...