This communication deals with the scientific problem of evaluating the similarity between two chemical systems, each described by a finite discrete set of elements/members, which are in turn p-dimensional vectors of chemical/biological descriptors. A variant of the Hausdorff measure, called Hausdorff-like similarity (Hs), is proposed aimed at taking into account information on all the elements ...

The biochemical properties of food allergens exert a large influence on how these allergens act when ingested, and determines important aspects such as cross-reactivity, lability to degradation during digestion or stability during processing of the food. One of the targets for biochemical characterization of food allergens is to establish a link between the biochemical data and the biological a...

Self-emulsifying compositions are the basis of oral drug delivery systems used to improve solubility and increase bioavailability active pharmaceutical ingredients that poorly soluble in aqueous medium gastric juice. Aim. To develop self-emulsifying using simvastatin as an ingredient. Materials methods. During development composition mixture, excipients, such solvents, co-solvents, surfactants ...

At present, there are practically no reference materials for values characterizing the beneficial effect of use petroleum products, which reduces efficiency metrological assurance processes products testing. In particular, certification by method monitoring technical characteristics is an ineffective procedure a number motor sets and benches. It necessary to assess stability such testing equipm...

In the work, composition of starting materials and reaction products was checked by chromatographic method. The purpose work is to study effect temperature on decomposition process propane-butane mixture at high temperatures. Qualitative analysis carried out method "witnesses", quantitative internal normalization. Spatial performed a DRON- 4.0 (CuKa - radiation) diffractometer, particle size sc...

Egg lecithin is a complex mixture of phosphatides that consists mainly of phosphatidylcholine and phosphatidylethanolamine, combined with various amounts of other substances such as triglycerides and fatty acids [1]. As pharmaceutical excipient lecithin is used in parenteral emulsions, liposomes and mixed micellar solutions. It has been proved, that aqueous dispersions of lecithin (Water-Lecith...

background thymus species are well known medicinal plants which the previous studies suggested the involvement of the opioid system in them. objectives this study aimed to investigate the effects of methanolic extract and essential oil of aerial parts of thymus daenensis (td), an endemic aromatic medicinal plant of iran, on morphine withdrawal syndrome in mice. materials and methods experiments...

population pattern in guilan province represents a dramatic increase in youth population. regarding high prevalence of substance use among them, its destructive effects and consequences and paucity of previous related studies, this research was performed to determine the prevalence of substance use among students of guilan university of medical sciences (gums). we conducted a cross-sectional st...

drug abuse has high co-morbidity with mental disorders, thus, controlling and treating it requires multimodal treatment intervention. this cross sectional study evaluates personality traits of 67 ïv heroin abusers in kashan prison. the utilized instruments included two parts: a demographic questionnaire and mmpï. the data obtained from the questionnaires were statistically analyzed by using fis...

results the χ2 test showed that the experimental and control groups significantly differed in relapse rates (χ2 = 6.30, df = 1, p < 0.001). in addition, the covariance analysis showed a significant difference between the two groups in resiliency enhancement at post-test (f = 33.76, p < 0.001) and follow-up (f = 37.67, p < 0.001). conclusion the results indicate that lifestyle training is effect...