The gene encoding mammary-derived growth inhibitor (MOGI), a protein previously purified from bovine mammary gland and shown to have modest antiproliferative activity for human breast cancer cells in vitro, is demonstrated to function as a potent tumor suppressor gene. Human breast cancer cells transfected with a MDGI expression construct exhibited differentiated morphology, reduced proliferati...

Copaifera langsdorffii, locally known as copaíba, is a valuable tropical tree with medicinal properties of its oil. We studied the genetic variation, genetic structure, and the mating system of trees in stands of C. langsdorffii (Leguminosae/Caesalpinioideae) located in an extensive area between the Pardo and Mogi-Guaçu basins in São Paulo State, Brazil, and their offspring, conserved in an ex ...

One of the greatest remaining problems in modern volcanology is the process by which volcanic eruptions are triggered. It is generally accepted that eruptions are preceded by magma intrusion [Sigurdsson and Sparks, 1978]. The degree of interaction between previously ponded magma in a chamber and newly intruded magma determines the nature and rate of eruption and also the chemistry of erupted la...

A 7 year time series of satellite radar images over Unimak Island, Alaska—site of Westdahl Volcano, Fisher Caldera, and Shishaldin Volcano—was processed using a model-free Persistent Scatterer Interferometry technique assisted by numerical weather prediction model. The deformation-only signals were optimally extracted from atmosphere-contaminated phase records. The reconstructed deformation tim...

(Fibre pits in wood of Xylopia emarginata Mart. (Annonaceae), Reserva Biológica e Estação Ecológica de MogiGuaçu, São Paulo State, Brazil). The influence of environmental conditions such as flooding areas on the anatomical features of wood is little known. The aim of this study was to compare the fibre pits in the stems and in the roots of Xylopia emarginata growing in a swampy forest and in a ...

Diabetes mellitus (DM) is a chronic disease caused by insufficient production of insulin by pancreatic gland and decrease in absorption glucose by the muscles in the systems and caused increase the concentration of glucose in blood [1]. It is also produced due to the hereditary characters. Due to increase glucose level in blood causes various deficiencies and hampers the normal Physiological ef...

Spatiotemporal correlations of the two-dimensional spring-block (Burridge-Knopoff) model of earthquakes are extensively studied by means of numerical computer simulations. The model is found to exhibit either a " subcritical " , " supercritical " or " near-critical " behavior, depending on the values of the model parameters. Transition between the " subcritical " and " su-percritical " regimes ...