www.johronline.com 83 | P a g e For Correspondence: [email protected] Received on: September 2014 Accepted after revision: October 2014 Downloaded from: www.johronline.com Introduction Sialolithiasis is a common disorder of salivary glands, it is a condition characterized by the obstruction of a salivary gland or its excretory duct due to formation of sialolith, further resulting in i...

Hyposalivation resulting from salivary gland dysfunction leads to poor oral health and greatly reduces the quality of life of patients. Current treatments for hyposalivation are limited. However, regenerative medicine to replace dysfunctional salivary glands represents a revolutionary approach. The ability of dispersed salivary epithelial cells or salivary gland-derived progenitor cells to self...

Epithelial myoepithelial carcinoma is a rare low grade malignant salivary gland neoplasm that most commonly occurs in the parotid gland but can also arise in minor salivary glands. We report a case of primary epithelial myoepithelial carcinoma of submandibular salivary gland in a 65 year old female who presented with left cheek swelling of six months duration. CT scan revealed a localized subma...

AIMS Molecular genetic changes involved in tumorigenesis and malignant transformation of human tumours are novel targets of cancer diagnosis and treatment. This study aimed to analyse the expression of putative tumour suppressor genes, FHIT and WT-1, and tumour rejection genes, BAGE, GAGE-1/2, MAGE-1, MAGE-3, and HAGE (which are reported to be important in human cancers), in salivary gland neop...

PURPOSE Primary Sjögren's syndrome is a multisystem autoimmune disease characterized by hypofunction of salivary and lacrimal glands and possible multi-organ system manifestations. Over the past 15 years, three sets of diagnostic criteria have been proposed, but none has included salivary gland ultrasonography. However, recent studies support its role in the diagnosis and prognostic evaluation ...

Xerostomia frequently arises in patients with head and neck malignancies that are treated by radiation. However, the mechanisms responsible for the destruction of the salivary gland remain unknown. We previously established a xerostomia model of mice and identified the pathway through which nitric oxide (NO) affects the pathogenesis of radiation-induced salivary gland dysfunction. Although the ...

Head and neck cancer is the fifth most common malignancy and accounts for 3% of all new cancer cases each year. Despite relatively high survival rates, the quality of life of these patients is severely compromised because of radiation-induced impairment of salivary gland function and consequential xerostomia (dry mouth syndrome). In this study, a clinically applicable method for the restoration...

Pleomorphic adenoma also known as “mixed tumor” is the most common neoplasm in major salivary glands. It is a benign tumor arises from the parotid gland in 84% of cases and represents 45% of parotid gland tumors [1]. Only 6.5% are found in the minor salivary glands [2]. Salivary gland tumors occurring in ectopic sites are rare and poorly understood; sometime we can find heterotopic tissue arisi...

Introduction. Lymphoepithelioma-like carcinoma (LELC) of the salivary gland is a rare tumor. Currently, surgery with or without radiotherapy is the recommended treatment for all salivary gland carcinomas. However, in contrast to other high-grade salivary gland carcinomas, LELCs are considered radiosensitive. There are only a few published reports of radiotherapy alone for the treatment of saliv...

BACKGROUND To determine the incidence and prevalence of salivary gland tumours in the province of Valparaíso, Chile. MATERIAL AND METHODS Retrospective review of salivary gland tumours diagnosed between the years 2000 and 2011 from four local pathology services. Information on demographics and histopathology were retrieved from the medical records. RESULTS The study sample consisted of 279 ...