نتایج جستجو برای: molecular approaches

تعداد نتایج: 1038909  

Journal: :Therapie 2000
S Laroche

There has been nearly a century of interest in the idea that information is stored in the brain as changes in the efficacy of synaptic connections on neurons that are activated during learning. The discovery and detailed report of the phenomenon generally known as long-term potentiation opened a new chapter in the study of synaptic plasticity in the vertebrate brain, and this form of synaptic p...

Journal: :Annual review of plant physiology and plant molecular biology 1999
Krishna K. Niyogi

The involvement of excited and highly reactive intermediates in oxygenic photosynthesis poses unique problems for algae and plants in terms of potential oxidative damage to the photosynthetic apparatus. Photoprotective processes prevent or minimize generation of oxidizing molecules, scavenge reactive oxygen species efficiently, and repair damage that inevitably occurs. This review summarizes se...

Journal: :Cell 2013
Taekjip Ha

Enormous mechanistic insight has been gained by studying the behavior of single molecules. The same approaches used to study proteins in isolation are now being leveraged to examine the changes in functional behavior that emerge when single molecules have company.

Journal: :Ciba Foundation symposium 1987

As known, adventure and experience about lesson, entertainment, and knowledge can be gained by only reading a book. Even it is not directly done, you can know more about this life, about the world. We offer you this proper and easy way to gain those all. We offer many book collections from fictions to science at all. One of them is this molecular approaches to human polygenic disease that can b...

2011
Dušanka Janežič Matej Praprotnik

In this contribution we will present the survey of our past and current endeavor on parallel approaches in molecular modeling algorithm development, for example, molecular dynamics (MD) simulation. In particular, we will describe the new split integration symplectic method for the numerical solution of molecular dynamics equations and methods for the determination of vibrational frequencies and...

Journal: :BioTechniques 2009
Amritha Jaishankar Kent Vrana

Stem cells are characterized by their ability to self-renew and differentiate into multiple adult cell types. Although substantial progress has been made over the last decade in understanding stem cell biology, recent technological advances in molecular and systems biology may hold the key to unraveling the mystery behind stem cell self-renewal and plasticity. The most notable of these advances...

Journal: :British medical bulletin 1996
N Craddock M J Owen

Major advances in molecular genetics over the last 15 years have made it possible to identify the genes responsible for human diseases using purely genetic approaches that do not require knowledge about disease pathophysiology. Many successes have been achieved for single gene disorders and methods are being adapted and refined for complex diseases. The main strategies include linkage and assoc...

Journal: :Expert opinion on drug safety 2004
Wendy J Bailey Roger Ulrich

An unprecedented interest in biomarker development has arisen from the increasing use of genomic information and high-throughput technologies in the field of drug development. Monitoring global cellular responses to perturbation due to disease, drug treatment or toxicity is achieved using molecular profiling methods such as DNA microarrays, proteomics and metabonomics. Unique fingerprints compo...

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