The major barrier to Alzheimer disease (AD) drug discovery and development in the biotechnology industry is scale. Most biotechnology companies do not have the personnel or expertise to carry a drug from the bench to the market. Much effort in the industry has been directed toward the elucidation of molecular mechanisms of AD and the identification of new targets. Advances in biotechnology have...

1Applied Microbiology and Molecular Biotechnology Research Group, Department of Molecular Biology and Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece 2Institute of Technology of Agricultural Products, Greek Agricultural Organization Demeter, 14123 Athens, Greece 3Department of Food Studies and Environmental Health, Faculty of Health Sciences, University of Malta, Msida ...

A New Look at Bacteriophage Genetic Networks Donald L. Court,* Amos B. Oppenheim, and Sankar L. Adhya Gene Regulation and Chromosome Biology Laboratory, National Cancer Institute at Frederick, Frederick, Maryland; Department of Molecular Genetics and Biotechnology, The Hebrew University-Hadassah Medical School, Jerusalem, Israel; and Laboratory of Molecular Biology, National Cancer Institute, B...

United Graduate School of Agricultural Sciences, Kagoshima University, Korimoto, Kagoshima 890-0065, Japan Division of Molecular Biotechnology, Center of Molecular Biosciences, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan Graduate School of Agriculture, Faculty of Agriculture, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan Tropical Biosphere Research Center, Univ...

Bioart is a creative practice that adapts scientific methods and draws inspiration from the philosophical, societal, and environmental implications of recombinant genetics, molecular biology, and biotechnology. Some bioartists foster inter- disciplinary relationships that blur distinctions between art and science. Others emphasize critical responses to emerging trends in the life sciences. Sinc...

Mahmoud Lotfy1 and Yousery E. Sherif2 1Associate Professor of Molecular Cell Biology & Immunology, Molecular and Cellular Biology Department, Genetic Engineering and Biotechnology Research Institute, Minufiya University, Sadat City, Minufiya, Egypt and Department of Applied Medical Sciences, Jouf University, Qurayat, 2Clinical Pharmacology Department, Faculty of Medicine, Mansoura University, M...

1Division of Human Gene Therapy, Departments of Medicine, Pathology, and Surgery 2Gene Therapy Center 3Department of Pathology 4Department of Obstetric and Gynecology 5Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA 6Department of Biotechnology and Molecular Medicine, A. I. Virtanen Institute for Molecular Sciences, University of Kuopio,...

Arabidopsis thaliana, a small annual weed belonging to the mustard family, has become a widely used model in plant genetic research. It has a small genome, short life cycle, and is easy to mutagenize. Identification of genes based on phenotype alone, often a rather difficult part of molecular genetic research, is easiest in this plant. Laboratories working on the "model" plant Arabidopsis thali...

Voltage-driven transport of double-stranded DNA through nanoscale pores holds much potential for applications in quantitative molecular biology and biotechnology, yet the microscopic details of translocation have proven to be challenging to decipher. Earlier experiments showed strong dependence of transport kinetics on pore size: fast regular transport in large pores (> 5 nm diameter), and slow...