The relationship between molecularly imprinted polymer (MIP) morphology and template-rebinding over a series of warfarin-imprinted methacrylic acid co(ethylene dimethacrylate) polymers has been explored. Detailed investigations of the nature of template recognition revealed that an optimal template binding was obtained with polymers possessing a narrow population of pores (~3-4 nm) in the meso...

Mimicking the selectivity and sensitivity of biological systems for sensor devices is of increasing interest in biomedical, environmental and chemical analysis. Synthetic materials with imprinted nanocavities, acting as highly selective artificial receptors, are a tailor-made solution in obtaining such a sensor. Incorporation of such molecularly imprinted polymers (MIPs) in a platform suitable ...

This paper presents novel handheld analyzer with disposable lab-on-chips for electrical detection of anesthetic propofol in human serum samples for clinical diagnostics. The developed on-chip biosensors are based on molecularly imprinted conducting polymer techniques. In this paper, we have designed, fabricated, and characterized the developed system with disposable lab-on-chips for detection o...

An important challenge for scientific research is the production of artificial systems able to mimic the recognition mechanisms occurring at the molecular level in living systems. A valid contribution in this direction resulted from the development of molecular imprinting. By means of this technology, selective molecular recognition sites are introduced in a polymer, thus conferring it bio-mime...

In this study, the synthesis and structural properties of a Molecularly Imprinted Polymer (MIP) and a Nonimprinted Polymer (NIP) bearing Fe-porphyrin moiety and amino acid moieties including Histidine (His), Tryptophan (Trp) and Arginine (Arg) are presented. The imprinted and nonimprinted polymeric beads were synthesized by suspension polymerization technique and characterized by using FT-IR sp...

Advancement in molecularly imprinted biomimetics has aided developing robust artificial recognition-based materials, which can be customized for bio/chemo-sensing of distinct molecules. The present study reports a simple one-step synthesis and analysis protein-imprinted polymer thin films as recognition element directly onto solid support. Dopamine been explored versatile functional monomer (MI...

A single bi-functional monomer, N,O-bismethacryloyl ethanolamine (NOBE), was used in precipitation polymerization system to synthesize molecularly imprinted polymer (MIP) microspheres. Highly specific binding sites were obtained for N-terminal protected neuropeptides, Boc-Leu-enkephalin and Pyr-Leu-enkephalin. The use of NOBE allowed binding sites to be formed in polymer microspheres that are a...