The isolation and preconcentration of estrogens from new types of biological samples (acellular and protein-free simulated body fluid) by molecularly imprinted solid-phase extraction has been described. In this technique, supramolecular receptors, namely molecularly imprinted polymers (MIPs) are used as a sorbent material. The recognition sites of MIPs were prepared by non-covalent multiple int...

STI571 (Gleevec, imatinib mesylate) exemplifies the successful development of a rationally designed, molecularly targeted therapy for the treatment of a specific cancer. This article reviews the identification of Bcr-Abl as a therapeutic target in chronic myelogenous leukemia and the steps in the development of an agent to specifically inactivate this abnormality. Issues related to clinical tri...

A total of 250 soil samples were taken from the forest, hazelnut, kiwi, vegetable, and meadow-rangeland areas in coastal regions Ordu province, Turkey. Entomopathogenic fungi isolated these using Galleria-bait method. Eighty-five fungal isolates samples, after which they morphologically molecularly identified. After morphological characterization, 64 out 85 identified molecularly. Based on mole...