As Francois Jacob tells it, one afternoon in September 1958, just back from New York, he walked into Jacque Monod’s office at the Pasteur Institute in Paris; he believed he had something exciting to discuss. But he found an unimpressed Monod brusquely dismissive. Tired from his flight, Jacob quickly gave up and went home to bed. The next day he returned re-energized and found an altogether more...

In 2013, Monod introduced a family of Thompson-like groups which provides natural counterexamples to the von Neumann–Day conjecture. We construct characterization conjugacy and an invariant use them compute centralizers in one group this family.

We formulate a field theory for the Haldane-Rezayi quantum Hall state and its variants. A new essential ingredient is a class of super Chern-Simons field.

The observation has been made repeatedly that the induced synthesis of many different enzymes can be inhibited by a wide variety of carbohydrates (Benzer, 1953; Cohn, 1957, 1958; Epps and Gale, 1942; Gale, 1943; Happold and Hoyle, 1936; Herzenberg, 1958; Monod, 1941, 1947, 1956; Monod and Cohn, 1952; Neidhardt and Magasanik, 1956). One of the most characteristic and potent of these carbohydrate...

Allosteric regulation is found across all domains of life, yet we still lack simple, predictive theories that directly link the experimentally tunable parameters of a system to its input-output response. To that end, we present a general theory of allosteric transcriptional regulation using the Monod-Wyman-Changeux model. We rigorously test this model using the ubiquitous simple repression moti...

To cite: Sharma S, Dubey SK, Kumar N, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-200936 DESCRIPTION A 62-year-old male patient presented with a symptom of haemoptysis for 15 days. There was history of pulmonary Koch’s for which he took complete treatment 11 years ago. In the CT scan of the chest, there was an irregular-shaped cavity in the right ...

ion of complex systems in various ways. Thus the subject of lumping of multicomponent, multireaction systems in petrochemical reaction engineering sought to find component clumps whose concentrations would serve to define their rates of change and to see the circumstances under which such simplifications would emerge. Naturally, linear reaction systems could be dealt with more elegance as, for ...

level: advanced M athematically modeling the kinetics of batch and continuous cultivation allows you to not only calculate and evaluate the effects of process parameters, but also to forecast those parameters and duration of cultivation to develop a costeffective production process. Mathematical modeling microorganism cultivation was intensively developed in the second half of the last century....