For decades, ultrasound technology has been widely used for diagnostic imaging in various clinical fields as well as in therapeutic applications. In recent years there has been considerable research devoted to sonoporation, a phenomenon where ultrasound increases cell membrane permeability. To study the biological effects of ultrasound in an in vitro setting, we have built a custom low-frequenc...

BACKGROUND How particular changes in functional morphology can repeatedly promote ecological diversification is an active area of evolutionary investigation. The African rift-lake cichlids offer a calibrated time series of the most dramatic adaptive radiations of vertebrate trophic morphology yet described, and the replicate nature of these events provides a unique opportunity to test whether c...

The rho proteins, p21rho, are ubiquitously expressed guanine nucleotide binding proteins with approximately 30% amino acid homology to p21ras, but their biochemical function is unknown. We show here that microinjection of constitutively activated recombinant rho protein (Val14rho) into subconfluent cells induces dramatic changes in cell morphology: 15-30 min after injection cells adopt a distin...

Few things remain static in natural systems and perhaps no better illustrated than by changes in the level of the ocean surface with respect to the land over Quaternary timescales. The position of sea level (ultimate base level) and changes of sea level over geological timescales represent important controls in the evolution of coastal environments, and as an agent of profound geomorphological ...

The complement and neutrophil defence systems, as major components of innate immunity, are activated during inflammation and infection. For neutrophil migration to the inflamed region, we hypothesized that the complement activation product C5a induces significant changes in cellular morphology before chemotaxis. Exposure of human neutrophils to C5a dose- and time-dependently resulted in a rapid...

OBJECTIVE Obstructive sleep apnea (OSA) causes hypoxemia and fragmented sleep, which lead to neurocognitive deficits. We hypothesised that focal loss of cortical gray matter generally within areas associated with memory processing and learning and specifically within the hippocampus would occur in OSA. METHODS Voxel-based morphometry, an automated processing technique for magnetic resonance i...

s 343 Folia Primatol 2004;75:341–354 consumption is occasional or limited for Microcebus, Cheirogaleus and Mirza, gum is the dominant food source for Phaner and Allocebus. Craniofacial shape variations were analysed using geometric morphometrics: methods based on landmarks identification (Procrustes superimpositions) were chosen for skull shape analysis, and methods based on outline decompositi...

To examine timed changes in the morphology of theca interna and granulosa cells of rabbit preovulatory follicles, mature female rabbits were injected with100 IU per kg of human chorionic gonadotropin (hCG) and follicles larger than1mn in diameter were excised for light and electron microscopic studies before and3, 6, 9and 12hr after hCG injection. Spindle-shaped theca interna cells had been tra...

We consider a thin film consisting of two layers of immiscible liquids on a solid horizontal (heated) substrate. Both the free liquid-liquid and the liquid-gas interface of such a bilayer liquid film may be unstable due to effective molecular interactions relevant for ultrathin layers below 100-nm thickness, or due to temperature-gradient-caused Marangoni flows in the heated case. Using a long-...

In the past, the kinetics of aggregation has been extensively studied. Aggregation rates were measured and calculated thanks to a population balance. Aggregate morphologies were measured or got by computer simulations. However, the link between the aggregation kinetics and the morphology changes with time is not so clear. The modelling of aggregation may be even more complex as restructuring of...