Gastrointestinal amyloidosis (GIA), a protein deposition disorder, represents a complex common pathway that encompasses multiple etiologies and presentations. It represents a significant diagnostic and treatment challenge. The disease results from the deposition of insoluble extracellular protein fragments that have been rendered resistant to digestion. GIA can be acquired or genetic, and most ...

OBJECTIVE To describe the prevalence of Coeliac disease (CD) and its clinical management. METHODS Narrative review. RESULTS Coeliac disease (CD) is an immune-mediated disorder that primarily affects the gastrointestinal (GI) tract. Recent data suggest a prevalence of about 1% in most Western countries, a figure that likely represents an increase in the prevalence of CD. Risk groups include ...

The disorders of gastrointestinal (GI) tract including intestine and colon are common in the patients with diabetes mellitus (DM). DM induced intestinal and colonic structural and biomechanical remodeling in animals and humans. The remodeling is closely related to motor-sensory abnormalities of the intestine and colon which are associated with the symptoms frequently encountered in patients wit...

IMPORTANCE: Since the outbreak of coronavirus disease 2019 (COVID-19), various digestive symptoms have been frequently reported in a significant portion of patients infected with the virus. It is well established that most patients with COVID-19 have fever along with respiratory signs and symptoms, such as cough and dyspnea. We present 36 cases with chief complaint of gastrointestinal (GI) symp...

Gastrointestinal (GI) motility function and its regulation is a complex process involving collaboration and communication of multiple cell types such as enteric neurons, interstitial cells of Cajal (ICC), and smooth muscle cells. Recent advances in GI research made a better understanding of ICC function and their role in the GI tract, and studies based on different types of techniques have show...

The interface between psychiatry and stress-related gastrointestinal disorders (GI), such as irritable bowel syndrome (IBS), is well established, with anxiety and depression the most frequently occurring comorbid conditions. Moreover, stress-sensitive Wistar Kyoto (WKY) rats, which display anxiety- and depressive-like behaviors, exhibit GI disturbances akin to those observed in stress-related G...

The gastrointestinal (GI) tract is the most common extranodal site affected by lymphoma, accounting for 5–20% of all cases.1 The incidence and location of primary GI lymphoma varies around the world. Overall, the most commonly involved sites are the stomach followed by the small bowel and ileocecal region.2 Concerning histological subtypes, mucosa-associated lymphoid tissue lymphoma is more com...

At first glance, it would seem peculiar to be discussing GI disorders in a psychiatric publication. However, functional GI disorders (FGIDs) represent a unique subset of GI disorders that have strong psychiatric implications beyond mere psychiatric comorbidity and/or psychosocial distress, which are indeed frequent concomitants of these disorders. There is increasing evidence that psychopharmac...

A growing amount of research indicates that abnormalities in the gastrointestinal (GI) system during development might be a common factor in multiple neurological disorders and might be responsible for some of the shared comorbidities seen among these diseases. For example, many patients with Autism Spectrum Disorder (ASD) have symptoms associated with GI disorders. Maternal zinc status may be ...