background: maternally administered opiates such as morphine represent a serious human health problem. opioid abuse may have unfavorable effects on reproductive organs. objective: the present study evaluates on the effects of morphine on structure and ultrastructure of uterus in balb/c mice. materials and methods: forty balb/c pregnant mice were divided into four groups: two experimental (i and...

background: routine oocytes cryopreservation remained an elusive technique in the wide ranges of available assisted reproductive technologies. the microtubules of oocytes are vulnerable to cryoprotectants and thermal change during cryopreservation. objective: the effects of a vitrification protocol were investigated on the spindle and chromosome configurations of mice oocytes cryopreserved at t...

phenobarbital is a phenobarbiturate used as a sedative, anticonvulsant, or hypnotic with the doses prescribed and can cause teratogenic effects. the goal of this study was to examine an alternative method for the recognition of the mechanism or the bimolecular potential changes in mice fetus caused by phenobarbital using ftir micro spectroscopy. the mice were injected with phenobarbital (120mg/...

salvia verticillata is one of the salvia species which possesses remarkable antioxidant activity. in the present study, we investigated the possible effects of hydro-alcoholic extract from salvia verticillata plant (sve) in various models of anxiety, depression and seizure in mice. mice were randomly divided into control (saline), sve-treated and standard treatment groups. the sve-treated group...

rosa damascena (rosaceae) has been found to act on central nervous system including the brain. several studies confirm that rosa damascena inhibits the reactivity of the hypothalamus and pituitary systems in rat and can suppress the reactivity of central nervous system. in traditional medicine the hypnotic effect of rose is also suggested. in the present study hypnotic effect of ethanolic, aque...

previous studies have shown that the extract of papaver rhoeas reduces morphine dependence, locomotor activity and reward. in present study, the effects of hydro-alcohol extract of papaver rhoeas on the tolerance to analgesic effects of morphine in mice have been investigated using tail flick method. subcutaneous (s.c.) administration of morphine (1, 2, 5 and 10 mg/kg) induced analgesia. howeve...

rosa damascena has been found to act on central nervous system including the brain. several studies confirm that r. damascena inhibits the activity of the hypothalamus and pituitary systems in rat and can suppress the central nervous system. in traditional medicine hypnotic effect of rose is also suggested. in this study, the hypnotic effect of the ethanol crude extract of r. damascena and its ...

background & objectives: the present investigation was designed to evaluate the post-treatment properties of the hydroalcoholic fruit extract of cassia fistula (golden shower tree) in male albino mice. materials & methods: biomarkers and histological liver and kidney alterations, aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), γ-glutamyl tra...

the objective of this study was to investigate whether or not the adverse effects of heat on sperm quality could be prevented by green tea extract (gte) administration. ninety adult male mice were randomly divided to two groups. the scrotum of each animal in the first group was immersed once for 20 min in a water bath maintained at 42 oc (heat group, h) and the second group (control group, c) w...

the virulence of pasteurella multocida (p. multocida) serotype a1 for chickens and mice was determined. groups of chicken and mice were exposed intramuscularly and intraperitoneally to various concentration of p. multocida broth culture, respectively. this strain was highly virulent for chickens so that those exposed to only 7 c.f.u. of the organism died in less than 24 hours. groups of mice ex...