Endogenous dynorphin signaling via the kappa-opioid receptor (KOR) in the nucleus accumbens (NAcc) powerfully mediates negative affective states and stress reactivity. Excitatory inputs from the hippocampus and amygdala play a fundamental role in shaping the activity of both NAcc D1 and D2 MSNs, which encode positive and negative motivational valences, respectively. However, a circuit-based mec...

Social networking has provided powerful new ways to find people, organize groups, and share information. Recently, the potential functionalities of the ubiquitous infrastructure let users form a mobile social network (MSN) which is discriminative against the previous social networks based on the Internet. Since a mobile phone is used in a much wider range of situations and is carried by the use...

Associated Infections Kyle Enfield, MD, MS; Costi D. Sifri, MD; Elizabeth Enfield, RN, MSN; Jessica Lewis, MD; Beth Quatrara, DNP, RN, CMSRN, ACNS-BC; Eve Giannetta, RN, BSN, CIC; Kristi Kimpel, RN, MSN; Kathleen Rea, RN, MSN; Department of Medicine, Division of Pulmonology, Hospital Epidemiology/Infection Prevention and Control, University of Virginia Health System, Charlottesville, VA; Depart...

Cytosine-guanine (CpG) containing oligodeoxynucleotides (ODN) have significant clinical potential as immunotherapeutics. However, limitations exist due to their transient biological stability in vivo, lack of specificity for target cells, and poor cellular uptake. To address these issues, we prepared amine magnetic mesoporous silica nanoparticles (M-MSN-A) then further modified with polyethylen...

Detecting network intrusion has been not only important but also difficult in the network security research area. In Medical Sensor Network(MSN), network intrusion is critical because the data delivered through network is directly related to patients’ lives. Traditional supervised learning techniques are not appropriate to detect anomalous behaviors and new attacks because of temporal changes i...

The density and distribution of spatial samples heavily affect the precision and reliability of estimated population attributes. An optimization method based on Mean of Surface with Nonhomogeneity (MSN) theory has been developed into a computer package with the purpose of improving accuracy in the global estimation of some spatial properties, given a spatial sample distributed over a heterogene...

Copyright © 2006 by the Wound, Ostomy and Continence Nurses Society J WOCN ■ May/June 2006 281 Barbara Pieper, PhD, RN, FAAN, CWOCN, CS, Professor/ Nurse Practitioner, College of Nursing, Wayne State University, Detroit, Mich. Mary Sieggreen, MSN, APRN, BC, CVN, Nurse Practitioner, Vascular, Harper University Hospital, Detroit, Mich. Barbara Freeland, MSN, APRN, BC, CDE, Clinical Nurse Speciali...

NGF, a trophic polypeptide, is necessary for the normal development and survival of certain populations of neurons in the CNS and PNS. In the CNS, cholinergic neurons of the basal forebrain magnocellular complex (BFMC) are prominent targets of NGF. During rat development, NGF increases the activity of ChAT in these neurons. In adult rats with experimental injury of axons in the fimbria-fornix, ...

Andy S. Jagoda, MD (Chair 2003-2006) Wyatt W. Decker, MD Jonathan A. Edlow, MD Francis M. Fesmire, MD Steven A. Godwin, MD Sigrid A. Hahn, MD (EMRA Representative 2003-2004, Committee member 2005-2006) John M. Howell, MD J. Stephen Huff, MD JoAnn Lazarus, RN, MSN, CEN (ENA Representative 2003) Thomas W. Lukens, MD, PhD Donna L. Mason, RN, MS, CEN (ENA Representative 2004-2006) Michael Moon, RN,...

C. difficile Infection Developing after Recent Hospitalization Christina Felsen, MPH; Gail Quinlan, RN, MSN; Cathleen Concannon, MPH; Anita Gellert, RN; Deborah Nelson, MSN, RN; Rebecca Tsay, MPH, MLS; Ghinwa Dumyati, MD; Elizabeth Dodds-Ashley, PharmD, MHS; New York Rochester Emerging Infections Program, University of Rochester Medical Center, Center for Community Health, Rochester, NY; Infect...